中成药治疗功能性腹胀的对比分析

A Comparative Analysis on Effect of Chinese Patent Medicines in Treating Functional Abdominal Distension

目的观察枳术宽中胶囊、达立通颗粒和六味安消胶囊三种中成药治疗功能性腹胀的临床疗效。方法将150例功能性腹胀患者随机分成3组各50例,其中枳术宽中组采用枳术宽中胶囊治疗,达立通组采用达立通颗粒治疗,六味安消组采用六味安消胶囊治疗,观察治疗1周、2周、4周后的有效率,以及治疗后1月、2月、4月的复发率。结果 3组治疗功能性腹胀都有显著的疗效,其中六味安消组的有效率高于其他2组,尤其要高于达立通组,但3组间疗效比较,差异均没有统计学意义(P>0.05)。结论枳术宽中胶囊、达立通颗粒和六味安消胶囊治疗功能性腹胀临床效果均比较理想,但各有侧重,且这3种中成药副作用少,安全性高,适合患者长期或间断服用。

Objective To compare the effect of three Chinese patent medicines, namely, Zhongzhi Kuanzhong capsule, Dalitong granule and Liuwei Anxiao capsule. Methods One hundred and fifty cases with functional abdominal distension were randomly and equally divided into three groups, and were treated by Zhongzhi Kuanzhong capsule, Dalitong granule and Liuwei Anxiao capsule,respectively. The response rate was observed after treatment for 1 week, 2 weeks and 4 weeks. The recurrence rate within one month,2 months and 4 months after treatment was observed. Results The 3 groups had obvious curative effect, the effective rate of the Liuwei Anxiao capsule group was higher than that of the other 2 groups, especially higher than Dalitong group, but the difference was not statistically significant（P0.05）. Conclusion Zhongzhi Kuanzhong capsule, Dalitong granule and Liuwei Anxiao capsule were all effective in treating functional abdominal bloating, and each medicine had unique advantages. These three Chinese patent medicines caused few side effects and exhibited high safety, and therefore they are suitable for long-term or intermittent use.