恢复期精神分裂症患者院内康复的临床研究

Clinical study of hospital rehabilitation in patients with schizophrenia during convalescence

目的探讨恢复期精神分裂症患者的院内康复效果。方法 116例恢复期精神分裂症患者,随机分为康复治疗组和常规对照组,各58例。常规对照组给予常规治疗,康复治疗组在常规治疗基础上给予康复治疗。比较两组患者的服药依从性、简明精神病评定量表(BPRS)总分及各因子得分,采用护士用住院患者观察量表(NOSIE)评定患者的治疗效果。结果康复治疗组患者的服药依从性明显优于常规对照组,差异有统计学意义(P<0.05)。治疗后康复治疗组焦虑抑郁、缺乏活力、思维障碍、激惹性得分及总分均低于常规对照组,差异有统计学意义(P<0.05)。康复治疗组患者的社会能力、社会兴趣、个人整洁、激惹、精神病性表现、退缩、抑郁评分分别为(22.65±2.47)、(27.88±6.34)、(30.49±5.65)、(9.58±2.06)、(6.34±2.37)、(7.23±2.89)、(3.76±1.27)分,均明显优于常规对照组的(15.67±2.53)、(11.03±5.46)、(12.29±3.67)、(13.47±1.36)、(8.87±2.69)、(13.79±4.21)、(5.68±1.25)分,差异有统计学意义(P<0.05)。结论对恢复期精神分裂症患者进行有效的院内康复治疗,能够改善恢复期精神分裂症患者的社会功能,明显提高恢复期精神分裂症患者的生活质量。

Objective To discuss the effect of hospital rehabilitation in patients with schizophreniaduring convalescence. Methods A total of 116 patients with schizophrenia during convalescence were randomly divided into rehabilitation group and normal control group, with 58 cases in each group. The normal control group received conventional therapy, and the rehabilitation group received rehabilitation therapy on the basis of conventional therapy. The medication compliance, brief psychiatric rating scale（BPRS） total score and each factor score were compared between the two groups, and the treatment effect of the patients was evaluated by nurses observation scale for inpatient evaluation（NOSIE）. Results The rehabilitation group had obviously better medication compliance than the normal control group, and the difference was statistically significant（P〈0.05）. After treatment, the rehabilitation group had obviously lower anxiety and depression, lack of vitality, mental disorders, irritability scores and total scores than normal control group, and their difference was statistically significant（P〈0.05）. The rehabilitation group had social competence, social interest, personal cleanliness, irritability, psychotic symptoms, withdrawal and depression scores respectively as（22.65±2.47）,（27.88±6.34）,（30.49±5.65）,（9.58±2.06）,（6.34±2.37）,（7.23±2.89） and（3.76±1.27） points, which were obviously better than（15.67±2.53）,（11.03±5.46）,（12.29±3.67）,（13.47±1.36）,（8.87±2.69）,（13.79±4.21） and（5.68±1.25） points in the normal control group, and their difference was statistically significant（P〈0.05）. Conclusion Effective hospital rehabilitation for hospital rehabilitation in patients with schizophrenia during convalescence can improve the social function of patients with chronic schizophrenia, and significantly improve their quality of life.