2型糖尿病患者颈动脉斑块形成的危险因素分析

The Analysis on the Risk Factors of Carotid Plaque Incidence of T2DM Patients

目的:分析2型糖尿病(T2DM)合并颈动脉斑块形成的危险因素。方法:筛选某社区医院辖区内所有2型糖尿病患者,根据超声诊断结果分为斑块组和非斑块组,调查2组患者的年龄、病程、体质指数(BMI)、腰臀比(WHR)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、总胆红素(TBIL)、尿素氮(BUN)、肌酐(CRE)、总胆固醇(TC)、甘油三酯(TG)、白细胞(WBC)、血小板(PLT)、血红蛋白(HGB)、空腹血糖(FPG)、糖化血红蛋白(HbAlc)等因素,分析各因素与斑块形成的相关性。结果:共纳入470例患者,单因素分析显示年龄、病程、BMI、WHR、ALT、AST、BUN、TC、WBC、PLT、HGB、FPG、HbAlc、LRI、RRI等因素均与颈动脉斑块有关(P<0.05);Logistic回归分析结果表明年龄、病程、FPG、HbA_(lc)、高血压病史是T2DM患者发生颈动脉斑块的独立危险因素(P<0.05)。结论:年龄、病程、FPG、HbA_(lc)、高血压病史是T2DM患者形成颈动脉斑块过程的危险因素。

Objective：To analyze the risk factors of T2DM patients complicated with carotid plaque incidence.Methods：All the patients in the area under a community hospital＇s jurisdiction were selected,and divided into the plaque group and non-plaque group according to the results of ultrasonic diagnosis,the age,the course,BMI,WHR,ALT,AST,TBIL,BUN,CRE,TC,TG,WBC,PLT,HGB,FPG and HbA1c of the patients in both groups were surveyed,and the connection between different factors and the plaque incidence was analyzed.Results：All 470 patients were included,the single factor analysis suggested that the factors including age,the course,BMI,WHR,ALT,AST,BUN,TC,WBC,PLT,HGB,FPG,HbA1c,LRI,RRI and others were related to carotid plaque （P〈0.05）;Logistic regression analysis results demonstrated that age,the course,FPG,HbA1c and the history of hypertension were the independent risk factors of T2DM patients suffering carotid plaque （P〈 0.05）.Conclusion：Age,the course,FPG,HbA1c and the history of hypertension are the risk factors in the course of T2DM patients happening carotid plaque.