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吸入性糖皮质激素对支气管哮喘的气道高反应性和炎性介质的影响 被引量:28

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摘要 支气管哮喘是临床常见的呼吸道疾病 ,临床表现为反复发作的喘息、气急、胸闷或咳嗽等症状,长期反复发作或感染可能导致慢性并发症 ,如慢性阻塞性肺疾病、支气管扩张、肺源性心脏病等 .支气管哮喘的病理改变主要是气道平滑肌的痉挛和气道炎症 ,而炎症在其中起着重要作用.本研究探讨了吸入糖皮质激素治疗支气管哮喘的效果及对患者相关肺功能、白细胞介素(I L )和肿瘤坏死因子α( TNF-α)水平的影响.
作者 王磊 郝海龙
出处 《山西医药杂志》 CAS 2017年第24期3068-3070,共3页 Shanxi Medical Journal
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  • 1Patelis A, Gunnbjornsdottir M, Malinovschi A, et aLPopulation-based study of multiplexed IgE sensitiza-tion in relation to asthma, exhaled nitric oxide,andbronchial responsiveness [J], Journal of Allergy andClinical Immunology,2012 ,130(2) : 397-402,e2.
  • 2Huang HR, Zhong YQ,Wu JF, et al. The associationbetween IFN-"/ and IL-4 genetic polymorphisms andchildhood susceptibility to bronchial asthma [ J 3.Gene,2012,494(1).96-101.
  • 3Kim HJ,Lee HJ, Jeong SJ,et al. Cortex mori radicisextract exerts antiasthmatic effects via enhancementof CD4 + CD25 + Foxp3 + regulatory T cells and inhi-bition of Th2 cytokines in a mouse asthma model[J].Journal of Ethnopharmacology,2011,138(1) :40-46.
  • 4Cakebread JA,Xu YH, Grainge C,et al. ExogenousIFN-(3 has antiviral and anti-inflammatory propertiesin primary bronchial epithelial cells from asthmaticsubjects exposed to rhinovirus[J]. Journal of Allergyand Clinical Immunology, 2011, 127 (5): 1148-1154 ,ell49.
  • 5Kool M,Willart MA,van Nimwegen M,et al. An un-expected role for uric acid as an inducer of T helper 2cell immunity to inhaled antigens and inflammatorymediator of allergic asthma [J]. Immunity, 2011,34(4):527-540.
  • 6Wang C. Rose-Zerilli MJ, Koppelman GH,et al. Evi-dence of association between interferon regulatoryfactor 5 gene polymorphisms and asthma [J]. Gene,2012,504(2):220-225.
  • 7Hardyman MA,Wilkinson E, Martin E, et al. TNF-a-mediated bronchial barrier disruption and regula-tion by src-family kinase activation [J]. Journal ofAllergy and Clinical Immunology ,2013,132(3) : 665-675,e8.
  • 8van der Wiel E, ten Hacken NH, Postma DS, et al.Small-airways dysfunction associates with respirato-ry symptoms and clinical features of asthma: a sys-tematic review [J]. Journal of Allergy and ClinicalImmunology,2013 ,131(3) : 646-657.
  • 9Medley H, Orozco S, Allen A. Efficacy and safetyprofile of fluticasone furoate administered once dailyin the morning or evening: a randomized, double-blind, double-dummy, placebo-controlled trial in a-dult and adolescent patients with persistent bronchi-al asthma [J]. Clinical Therapeutics, 2012,34 ( 8) *1683-1695.
  • 10Mirsadraee M, Mozaffari A, Attaran D. Prevalence of asthma in children of chemical warfare victims[J]. Iranj pediatr, 2011, 21(3): 294-300.

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