每日透析用于诱导期血液透析的可行性及优势性分析

The Feasibility and Superiority Analysis of Daily Hemodialysis for Hemodialysis During Induction Period

目的 探究每日透析在血液透析诱导期的可行性及优势性.方法 选择收治的49例慢性肾衰竭尿毒症患者作为研究对象,按入院先后分为常规透析（conventional hemodialysis,CHD）组（n=23）和每日透析（daily hemodialysis,DHD）组（n=26）.CHD组患者在透析诱导期给予常规血液透析治疗,DHD组患者则在透析诱导期间给予每日透析.对比两组患者在透析前后各项临床指标变化以及失衡综合征的发生情况.结果 透析前,两组患者的各生命体征指标及各项凝血功能指标比较差异无统计学意义（P〉0.05）.诱导透析后,DHD组的HR、SBP以及DBP水平明显低于CHD组,其SpO2水平明显高于CHD组;两组患者仅有APTT出现明显下降,CHD组的下降幅度明显大于DHD组（P〈0.05）.诱导透析期间,DHD组患者的失衡综合征发生率为7.69%,低于CHD组（30.43%）（P〉0.05）.同时在诱导透析之后,DHD组的各项躯体及心理评分均明显低于CHD组（P〈0.05）.结论 在透析诱导期间给予患者以每日透析,能够使其各项生命体征趋于稳定,失衡综合征的发生率明显减少,为其提供了一个较为舒适、平稳、安全的血液净化过程,可以将其作为透析诱导期的首选透析方案替代常规血液透析.

Objective To research the feasibility and superiority of daily hemodialysis for hemodialysis during induction period. Methods We selected 49 cases of chronic renal failure uremia patients in our hospital as the research object, according to admission, they were divided into the CHD group （n=23） and the DHD group （n=26）. The patients in the CHD group were given routine hemodialysis during induction of dialysis, while the patients in the DHD group were given daily hemodialysis during induction of dialysis. We compared the changes in clinical indicators and the incidence of imbalance syndrome in two groups before and after dialysis. Results Before dialysis, there were no significant differences in vital signs and coagulation function indexes between the two groups （P〉0.05）. After induction dialysis, the levels of HR, SBP and DBP in the DHD group were significantly lower than those in the CHD group, and the SpO2 level was significantly higher than that in the CHD group; Only APTT showed a marked decline in two groups, and the decrease in the CHD group was significantly greater than that in the DHD group （P〈0.05）. During induction dialysis, the incidence of imbalance syndrome in the DHD group was 7.69%, lower than that in the CHD group （30.43%） （P〉0.05）. After induction dialysis, the physical and psychological scores of the DHD group were significantly lower than those of the CHD group （P〈0.05）.Conclusion Giving patients daily hemodialysis during induction period can make the vital signs stable,incidence of imbalance syndrome significantly reduced, and to provide a more comfortable, stable and safe blood purification process to the patients, which can be used as the preferred dialysis scheme to replace conventional hemodialysis.