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高迁移率族蛋白在高钙尿相关炎症反应中的作用研究进展 被引量:1

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摘要 高钙尿是含钙肾结石形成的危险因素,能直接诱导肾小管上皮损伤和增加炎症因子表达.细胞损伤和炎症反应被认为是结石形成的重要因素.高迁移率族蛋白(high mobility group box 1,HMGB1)是一种炎症介质,生理作用复杂,在结石患者尿液中生成增多.HMGB1在高钙尿和含钙肾结石相关炎症反应中的作用值得深入研究.
出处 《国际泌尿系统杂志》 2017年第6期945-948,共4页 International Journal of Urology and Nephrology
基金 国家自然科学基金(81660125)
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