经直肠超声下穿刺活检对老年前列腺特异性抗原灰区前列腺癌的诊断价值

Diagnostic value of transrectal puncture biopsy under ultrasound for elderly prostate cancer of prostate-specific antigen gray zone

目的探讨经直肠超声下穿刺活检对老年前列腺特异性抗原灰区前列腺癌的诊断价值。方法选择2014年7月~2017年7月在我院接受治疗的120例疑似老年前列腺特异性抗原灰区前列腺癌患者作为研究对象,并给予随机分组,对照组60例,给予普通直肠超声穿刺;观察组60例,给予经直肠超声造影穿刺,对两组患者穿刺情况、诊断阳性率、穿刺阳性针数以及不良反应发生情况进行综合评价。结果观察组平均穿刺针数为(7.93±2.46)针,与对照组的(8.23±1.42)针比较差异无统计学意义(P>0.05);观察组与对照组患者前列腺癌阳性率分别为16.7%、15.0%,两组前列腺癌阳性率比较差异无统计学意义(P>0.05);病理组织结果显示观察组阳性针数占12.3%,显著高于对照组的4.5%(P<0.05);穿刺后观察组不良反应率为10.0%,与对照组(26.7%)比较差异有统计学意义(P<0.05)。结论采用经直肠超声下穿刺活检诊断老年前列腺特异性抗原灰区前列腺癌,具有较高的检出率,安全性高,值得推广应用。

Objective To investigate the diagnostic value of transrectal puncture biopsy under ultrasound in the diagnosis of elderly prostate cancer of the prostate-specific antigen gray zone. Methods A total of 120 cases of suspected elderly prostate cancer of prostate-specific antigen gray zone were selected as the study subjects, and were randomly divided into groups. The control group of 60 cases was given general rectal ultrasound and puncture; the observation group of 60 cases was given transrectal ultrasound contrast and puncture. The condition of puncture, positive rate of diagnosis, the number of positive punctures and adverse reactions were comprehensively evaluated in both groups. Results The average number of puncture needle in the observation group was（7.93±2.46）. Compared with the control group（8,23± 1.42）, there was no statistically significant difference（P〉0.05）; the positive rates of prostate cancer in the observation group and the control group were 16.7% and 15.0%, and there was no statistically significant difference between the two groups in the positive rate of prostate cancer（P〉0.05）; the results of pathology showed that the positive number of needle in the observation group accounted for 12.3%, which was significantly higher than that of 4.5% in the control group（P〈0.05）. The rate of adverse reactions after puncture in the observation group was 10.0%. Compared with that of 26.7% in the control group, the difference was statistically significant（P〈0.05）. Conclusion The transrectal puncture. biopsy under ultrasound in the diagnosis of elderly prostate cancer of the prostate-specific antigen gray zone has a higher detection rate, and the safety is high, which is worthy of promotion the application.