补肾化瘀方合逍遥散加减治疗青春期多囊卵巢综合征临床研究

Clinical Study of Using Bushen Huayu Formula Combined with Xiaoyao Powder Treating Adolescent Polycystic Ovary Syndrome

目的:观察补肾化瘀方合逍遥散加减治疗青春期多囊卵巢综合征(PCOS)的疗效。方法:选取符合纳入标准的青春期多囊卵巢综合征患者35例,给予补肾化瘀方合逍遥散加减治疗3个月经周期,观察患者治疗前后的月经情况、血清睾酮(T)、黄体生成素(LH)/卵泡刺激素(FSH)及超声下双侧卵巢体积和卵泡数目的变化情况。结果:治疗后患者月经情况明显改善,治愈11例(31.43%),好转16例(45.71%),无效8例(22.86%),总有效率77.14%;T、LH/FSH、卵泡数目和卵巢体积均较治疗前降低(P<0.05)。结论 :补肾化瘀方合逍遥散加减可改善青春期PCOS患者的月经情况,使LH/FSH及T水平下降,减少卵泡数目,缩小卵巢体积。

Objective：To observe the clinical effect of Bushen Huayu formula combined with Xiaoyao powder on adolescent polycystie ovary syndrome（PCOS）. Methods：There were 35 patients with adolescent PCOS meeting the inclusion criteria. The patients were treated with Bushen Huayu formula combined with Xiaoyao powder for 3 months. The state of menstruation,the level of serum testosterone,the ratio of luteinizing hormone（LH）/follicle-stimulating hormone（FSH）,the volume of bilateralovaries and the number of follicles were observed. Results：The state of menstruation was improved significantly. 11 cases were eured（31.43%）,16 cases were improved（45.71%） and 8 cases of no effect（22.86%）,with the total effective rate of 77.14%. After the treatment,serum testosterone level,LH/FSH,the volume of ovary and the number of follicles were lower than those before treatment（P〈0.05）. Conclusion：Bushen Huayu formula combined with Xiaoyao powder can improve the menstruation of patients with adolescent PCOS,reduee the level of LH/FSH,serum testosterone ,the number of follicles and the volume of ovary.