气管支气管脂肪瘤的临床分析并1例报道

Clinical analysis and report of 1 case with tracheal and bronchial lipoma

目的探讨气管支气管脂肪瘤的临床特点及诊治措施。方法收集国内发表的具有病理学证据的气管支气管脂肪瘤的相关病例53例,并结合2011—2016年郑州大学第一附属医院收治的10例确诊为气管支气管脂肪瘤患者的临床资料,对气管支气管脂肪瘤的临床特点进行回顾性分析。结果 63例患者中男50例,女13例,年龄19~78岁,平均(55±11)岁。病史10 d^30 a。临床表现不典型,多以咳嗽、咳痰、胸闷气促就诊。47例行胸部CT均可发现异常占位。支气管镜下切除23例,外科手术切除36例。结论气管支气管脂肪瘤好发于中年男性,生长缓慢,症状与肿瘤的大小及部位有关。胸部CT及支气管镜检查对于早期诊断气管支气管脂肪瘤有重要意义,支气管镜下的介入治疗是气管支气管脂肪瘤的首选治疗方式。

Objective To explore the clinical characteristics, the diagnosis and treatment of tracheal and bronchial lipoma. Methods An analysis was performed to collect the relevant cases of domestic published for 53 tracheal and bronchial lipoma with pathological evidence, and combine with the clinical data for 10 patients of tracheal and bronchial lipoma occurring from 2011 to 2016 years in the First Affiliated Hospital of Zhengzhou University. Results Of the 63 cases, 50 cases were male patients, 13 cases were female patients. The age ranged from 19 to 78 years old and the over all mean age was （55±11 ） years. The onset time ranged from 10 days to 30 years. The clinical manifestations were atypical, more cough, expectoration, thorax or dyspnea to be performed. 47 cases of chest CT could be found abnormal. Bronchoscopic resection was applied for 23 patients and there were 36 cases treated by surgical operation. Conclusions Tracheal and bronchial lipoma generally occurs in middle - aged male and grows slowly. The clinical symptoms correlate with the size and location of tumor. Chest CT or bronchoscopy is impor- tant for early diagnosis of tracheal and bronchial lipoma. Interventional therapy under bronchoscope is the first choice of treatment for tracheal and bronchial lipoma.