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己酮可可碱对脑缺血-再灌注诱导的多形核细胞浸润的影响 被引量：3

Inhibitory effect of pentoxifylline on polymorphonuclear leukocyte infiltration into cerebral focal ischemia tissue
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作者 储智勇 芮耀诚 张蕾 陆波
机构地区 海军医学研究所 第二军医大学药学院药理教研室
出处 《中国药理学通报》 CAS CSCD 北大核心 2002年第4期472-474,共3页 Chinese Pharmacological Bulletin
基金 国家自然科学基金资助项目 No 3 9670 83 2
关键词 己酮可可碱 脑缺血 再灌注 多形核细胞浸润 PMN MPO activity assay brain ischemia, focal pentoxifylline middle cerebral artery occlusion
分类号 R972.4 [医药卫生—药品] R743.31 [医药卫生—神经病学与精神病学]
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参考文献15

  • 1Stanimirovic D;Satoh K.Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation[J],2000(01).
  • 2Issekutz AC.Vascular response during acute neutrophilic inflammation. Their relationship to in vivo neutrophil emigration,1981.
  • 3Kochanek PM;Hallenbeck JM.Polymorphonuclear leukocytes and monocytes/macrophages in the pathogensis of cerebral ischemia and stroke,1992.
  • 4Barone FC;Hillegass LM;Price WJ.Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification[J],1991.
  • 5Windmeier C;Gressner AM.Pharmacological aspects of pentoxifylline with emphosis on its inhibitory actions on hepatic fibrogenesis,1997.
  • 6Vincenti F;Danovitch GM;Neylan JF.Pentoxifylline dose not prevent the cytokine-induced first dose reaction following OKT3-a randomized,double-blind placebo-controlled study[J],1996(04).
  • 7Chu ZY;Rui YC.Effects of pentoxifylline and protein Kinase C inhibitor on phorbol ester-induced intercellular adhesion molecule-1 expression in brain microvascular endothelial cells,1999(08).
  • 8Enrigue ZL;Philip RW;Sara C;Robert C.Reversible middle cerebral artery occlusion without craniectomhy in rats,1989(01).
  • 9Zhang RL;Chopp M;Jiang N.Anti-intercellular adhesion molecuyle-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the wistar rat,1995(08).
  • 10Bradley PP;Priebat DA;Christensen RD;Rothstein G.Measurement of cutaneous inflammation:estimation of neutrophil content with an enzyme marker[J],1982.

同被引文献28

  • 1刘广义,解建波,宋金明.脑缺血再灌注后bcl-2、caspase-3 mRNA水平表达与大脑皮质及纹状体区炎性细胞浸润[J].中国老年学杂志,2005,25(4):428-430. 被引量：1
  • 2陈伟峰,刘德红.已酮可可碱对大鼠全脑缺血再灌注后炎症反应的影响[J].中国热带医学,2005,5(8):1647-1649. 被引量：2
  • 3王怀瓯,魏伟,林坚,许璟.己酮可可碱对抗脑缺血再灌注损伤的实验研究[J].温州医学院学报,2006,36(3):201-203. 被引量：3
  • 4Guerrero-Romero F, Rodriguez-Moran M, Paniagua-Sierra JR et al. Pentoxifylline reduces proteinuria in insulin-dependent and non insulin-dependent diabetic patients[J]. Clin Nephrol, 1995,43(2):116-21.
  • 5Ito Y, Aten J, Bende RJ et al. Expression of connective tissue growth factor in human renal fibrosis[J]. Kidney Int, 1998,53(4):853-61.
  • 6Wahab NA, Yevdokimova N, Weston BS et al. Role of connective tissue growth factor in the pathogenesis of diabetic nephropathy[J]. Biochem J, 2001,359(Pt 1):77-87.
  • 7Riser BL, Denichilo M, Cortes P et al. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis[J]. J Am Soc Nephrol, 2000,11(1):25-38.
  • 8Guerrero-Romero F, Rodriguez-Moran M, Paniagua-Sierra JR et al. Pentoxifylline reduces proteinuria in insulin-dependent and non insulin-dependent diabetic patients[J]. Clin Nephrol,1995,43(2):116-21.
  • 9Gunter Wolf. Molecular mechanisms of diabetic mesangial cell hypertrophy: A proliferation of novel factors[J]. J Am Soc Nephrol, 2002,13(10):2611-3.
  • 10Lin SL, Chen RH, Chen YM et al. Pentoxifylline inhibits platelet-derived growth factor-stimulated cyclin D1 expression in mesangial cells by blocking Akt membrane translocation[J]. Mol Pharmacol, 2003,64(4):811-22.

引证文献3

二级引证文献10

中国药理学通报
2002年 第4期

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