温阳益气方足浴对老年人轻度认知功能障碍的影响

Influence of the Foot Bath with Yang-Warming,Qi-Replenishing and Blood-Activating Prescription on Senile Mild Cognitive Impairment

目的:观察温阳益气活血方足浴对老年人轻度认知功能障碍的影响。方法:研究对象来自2011年7月—2012年7月浦东新区社区老年人轻度认知障碍(MCI)的流行病学调查,4家社区卫生服务中心建档的194例,44例未签署知情同意书,30例不符合诊断标准,共120例研究对象入组,随机分为对照组62例和干预组58例。对照组和干预组患者均给予轻度认知障碍相关知识的健康宣教,干预组另给予自拟温阳益气活血方足浴治疗。两组均随访1 a,于入组时及1 a后予以简易智力状态检查(Mini-mental state examination,MMSE)和蒙特利尔认知评估量表(MoCA)评定认知功能。结果:干预组干预后MoCA总分比治疗前升高,差异有统计学意义(P<0.05);干预组干预后视空间与执行功能、注意、延迟回忆和定向等评分均提高,差异有统计学意义(P<0.05);对照组延迟回忆和定向等评分均提高,差异有统计学意义(P<0.05)。结论:温阳益气活血方足浴能改善老年人轻度认知功能障碍程度。

Objective ： To observe the influence of Yang-Warming, Qi-Replenishing and Blood-Activating Prescription on senile mild cognitive impairment （MCI）. Methods：Patients with senile MCI in the Pudong New District Community between July 2011 and July 2012 were conducted epidemiological investigation. Among the 194 cases with bookbuilding in four community health service centers,44 cases didn＇t sign the informed contents,30 cases not accorded with the diagnostic criteria, and eventually 120 cases were as the research objects and randomized into control group （62 cases） and intervention group （58 cases）. Both groups were given health education on MCI while intervention group were additionally given self-formulated Yang-Warming, Qi-Replenishing and Blood-Activating Prescription. Both groups were conducted follow-up for I a, MMSE and MoCa were determined at the time of grouping and after 1 a. Results：The total score of MoCA after intervention in intervention group increased compared with before treatment;the difference had statistical significance （P 〈 0.05 ）. Scores of delayed memory and orientation in control group in- creased,with statistical difference （ P 〈 0.05 ）. Conclusion： Yang-Warming, Qi-Replenishing and Blood-Activating Prescription can improve the degree of senile MCI.