中风2号对缺血性中风风痰瘀阻证复发率的影响

Influence of Stroke No.2 on the Recurrence Rate of Syndrome of Wind Phlegm and Blood Stasis in Ischemic Apoplexy

目的:观察中风2号对缺血性中风风痰瘀阻证复发率的影响。方法:选取符合纳入标准的缺血性中风风痰瘀阻证患者200例,按随机数字表法分为对照组和治疗组,对照组102例,治疗组98例。对照组给予阿司匹林肠溶片0.1 g,口服,每晚1次;阿托伐他汀钙片20 mg,口服,每晚1次。治疗组在对照组的基础上加服中风2号(姜半夏10 g,胆南星6 g,石菖蒲10 g,红景天10 g,红花10 g,地龙10 g,乌梢蛇10 g)治疗,每天3次。分别于6个月、12个月、18个月、24个月观察中风的复发率,在观察结束时对患者的中医证候疗效、中医证候积分、Barthel指数、血脂四项等进行检测。结果:对照组复发率为27.4%,治疗组复发率为14.2%,两组比较,差异有统计学意义(P<0.05);中医证候疗效比较,对照组证候疗效为78.43%,治疗组证候疗效为93.88%,两组比较,差异有统计学意义(P<0.05);治疗后两组患者Barthel指数、中医证候积分、血脂四项比较,差异均有统计学意义(P<0.05)。结论:中风2号能降低缺血性中风风痰瘀阻证患者的复发率,且能够明显提高患者中医证候疗效、Barthel指数和中医证候积分,改善患者血脂水平。

Objective： To observe the influence of Stroke No. 2 on syndrome of wind phlegm and blood stasis in ischemic apoplexy.Methods： Chose 200 patients of syndrome of wind phlegm and blood stasis in ischemic apoplexy who met the acceptance standard,divided them into the control group and the treatment group randomly. Patients in control group took in aspirin enteric-coated tablet0. 1 g by oral administration in the evening and atorvastatin calcium tablet 20 mg by oral administration in the evening; patients in treatment group,on the basis of control group,took in Stroke No. 2 additionally,the composition： Jiangbanxia（ Pinellia Rhizoma prepared by ginger） 10 g,Dannanxing（ Bile Arisaema） 6 g,Shichangpu（ Acorus Tatarinowii） 10 g,Hongjingtian（ Rhodiola Rosea L.） 10 g,Honghua（ Carthamus Tinctorius L.） 10 g,Dilong（ Geosaurus） 10 g,Wushaoshe（ Zaocys Dhumnades） 10 g by oral administration,three times a day. Recurrence rate was observed after 6 months,12 months,18 months,24 months. At the end of the observation,the curative effect of TCM syndrome,TCM syndrome scores,Barthel index,four items of lipid,etc,were checked. Results： Recurrence rate of control group was 27. 4%,and the treatment group was 14. 2%. Comparison of the two groups was of statistical significance（ P〈0. 05）. As for curative effect of TCM syndrome comparison,control group was 78. 43% and treatment group was 93. 88%; by comparison,the difference was of statistical significance（ P〈0. 05）. As for the comparisons of Barthel index,TCM syndrome scores and four items of lipid of the two groups after treatment,the differences were of statistical sig-nificance（ P〈0. 05）. Conclusion： Stroke No. 2 can reduce the recurrence rate of wind phlegm and blood stasis in ischemic apoplexy,improve curative effect of TCM syndrome,Barthel index and TCM syndrome scores significantly,and improve lipid level.