摘要
目的:对儿童使用抗感染药物发生不良反应(ADR)的规律和特点进行探讨,为临床药物使用提供参考。方法:收集我院2013-2016年105例患儿抗感染药物引起的ADR报告,分别从患儿基本信息、ADR临床表现、药物种类等多方面探讨原因,并提出针对性的预防措施。结果:静脉给药易发生ADR;药物中以头孢菌素类所致ADR较多;ADR累及器官主要集中在皮肤及附件损害。结论:儿童在临床中使用抗感染药物时更应警惕ADR。
Objective: To investigate the characteristics and rules of the adverse reactions caused by anti-infectives among children and provide references for clinical drug use. Methods: The study was made to collect the 105 case reports of adverse reactions caused by anti-infectives in our hospital from 2013 to 2016. The reasons from the children's information,ADR clinical manifestations,the drug kinds were analyzed,and putted forward relevant preventive measures. Results: Intravenous infusion was easy to cause adverse reactions. Most cases of ADR were caused by cephalosporins. The common manifestation was skin and accessory damage. Conclusion:The clinical application of antibiotics should pay more attention to adverse reaction.
出处
《儿科药学杂志》
CAS
2018年第1期46-48,共3页
Journal of Pediatric Pharmacy
关键词
儿童
抗感染药物
不良反应
children
anti-infectives
adverse reactions