健康体检人群脂肪肝患者合并胆囊疾病流行特征及危险因素的相关分析

Analysis on epidemiological characteristics and risk factors of fatty liver complicating gallbladder diseases among healthy physical examination people

目的分析健康体检人群中脂肪肝患者合并胆囊疾病的流行病学特征,探讨其发病的危险因素。方法选取2011年6月至2015年6月在郑州大学第一附属医院体检中心行腹部彩色多普勒超声检查的7 364例体检者为研究对象,根据结果分为4组,脂肪肝合并胆囊疾病组、单纯脂肪肝组、单纯胆囊疾病组和非脂肪肝非胆囊疾病组,采用Logistic回归模型分析相关因素对脂肪肝患者合并胆囊疾病的影响。结果胆囊疾病在脂肪肝患者中的患病率显著高于无脂肪肝的人群(P<0.05)。Logistic回归模型显示,经常不食早餐、油腻饮食、多肉食、多甜食、多饮茶、性别(女性)、年龄、低密度脂蛋白(LDL-C)是脂肪肝合并胆囊疾病的独立危险因素(P<0.05)。结论不良生活习惯是脂肪肝合并胆囊疾病的独立危险因素。

Objective To analyze the epidemiological characteristics of fatty liver complicating gallbladder diseases among the people undergoing healthy physical examination and to investigate its onset risk factors. Methods A total of 7 364 subjects under- going abdominal color Doppler ultrasonography in the physical examination center of this hospital from June 2011 to June 2015 were selected as the study subjects and divided into 4 groups according to the examination results, fatty liver complicating gallbladder dis- ease group, simple fatty liver group, simple gallbladder diseases group and non-fatty liver and non-gallbladder disease group. The Logistic regression model was used to analyze the influence of related factors on the patients with fatty liver complicating gallblad- der diseases. Results The prevalence rate of gallbladder diseases in the patients with fatty liver ia significantly higher than that in the patients without fatty liver（P-0.05）. The multivariate Logistic regression model statistical analysis results showed that often skip breakfast,greasy food, eating more meat, eating much sweet food, dirking more tea, gender （female）, age and LDL-C were the independent risk factors for fatty liver complicating gallbladder diseases（P（0.05）. Conclusion The unhealthy living habits were the independent risk factors for fatty liver complicating gallbladder diseases.