摘要
目的分析精神分裂症患者应用利培酮后的不良反应发生情况,为精神科安全用药提供参考。方法随机抽取我院2016年1月至2016年12月收治的服用利培酮的精神分裂症患者100例进行回顾性分析。结果利培酮不良反应发生率为78%,主要为锥体外系反应、心血管系统反应、失眠、焦虑、体重增加、血清催乳素升高等。结论利培酮作为新型非典型抗精神病药物,目前在临床广泛应用,但是它的不良反应发生率仍然较高,涉及多个系统、器官,应引起医务人员的高度重视,做到早期预防、密切观察、准确判断、及时干预。
OBJECTIVE To analyze the incidence of adverse reactions of risperidone in patients with schiz- ophrenia, and to provide reference for safe drug use in psychiatric department. METHODS 100 schizophren- ic patients taking risperidone in our hospital from Janu- ary 2016 to December 2016 were randomly selected for retrospective analysis. RESULTS The incidence of risperidone adverse reaction was 78%, mainly being of extrapyramidal reaction, cardiovascular system response, insomnia, anxiety, weight gain, high serum prolactin lev- el etc. CONCLUSION As a new atypical antipsychot- ic drug, risperidone was widely used in clinical practice, but the incidence of adverse reactions was still high,in- volving multiple systems and organs, which should cause medical staff to pay high attention to early prevention, close observation, accurate judgement and timely inter- vention.
出处
《海峡药学》
2017年第12期267-268,共2页
Strait Pharmaceutical Journal
关键词
利培酮
不良反应
分析
risperidone
adverse reaction
analysis
