平肝定眩茶联合氨氯地平治疗肝阳上亢型高血压56例临床观察

Clinical observation of Pinggan Dingxuan Tea combined with Amlodipine in the treatment of 56 cases of hypertension of upper hyperactivity of liver Yang type

目的 :观察平肝定眩茶联合氨氯地平治疗肝阳上亢型高血压的临床疗效。方法 :收集2016年6月至2017年5月收治的原发性高血压肝阳上亢型患者56例,分为对照组28例,予口服苯磺酸氨氯地平5 mg/次,1次/d;观察组28例,在对照组治疗基础上给予平肝定眩茶治疗。治疗30 d后比较两组疗效。结果 :治疗后两组SBP和DBP水平均显著低于治疗前(P<0.05),且观察组显著低于对照组(P<0.05);治疗后观察组眩晕、头痛、急躁易怒、面红、目赤等中医证侯积分均显著低于治疗前(P<0.05),而对照组治疗前后除了眩晕、头痛症状有明显改善(P<0.05),其余中医证侯积分差异均不显著(P>0.05),两组间比较有统计学意义(P<0.05);观察组总有效率为92.85%,对照组总有效率为82.14%,两组比较差异有统计学意义(P<0.05)。结论 :平肝定眩茶联合氨氯地平可有效提高肝阳上亢型高血压患者的临床疗效。

Objective： To observe the clinical effect of Pinggan Dingxuan Tea combined with Amlodipine in thetreatment of hypertension of upper hyperactivity of liver yang type. Methods： From June 2016 to May 2017 56 cases of essentialhypertension of upper hyperactivity of liver Yang type treated in our hospital were collected and divided into a control group of 28cases who were given oral Amlodipine Besylate 5 mg/ time, 1 time /d, and an observation group of 28 cases who were treated withPinggan Dingxuan Tea on the basis of the control group. After 30 days of treatment, the efficacy of the two groups was compared.Results： After treatment, the levels of SBP and DBP in the two groups were significantly lower than those before treatment（P 〈 0.05）, and the observation group was significantly lower than the control group （P 〈 0.05）. After treatment, dizziness,headache, irritability, flushed face, hot eyes and TCM syndrome scores were significantly lower than those before treatment inthe observation group （P 〈 0.05）, and in addition to dizziness and headache symptom that were improved significantly before andafter treatment （P 〈 0.05）, there was no significant difference in other TCM syndrome scores in the control group （P 〉 0.05）, andthe difference between the two groups was statistically significant （P 〈 0.05）. The total effective rates of the observation groupand the control group were was 92.85% and 82.14%, and the difference between the two groups was statistically significant （P 〈0.05）. Conclusion： Pinggan Dingxuan Tea combined with Amlodipine can effectively improve clinical effects of hypertension of upper hyperactivity of liver yang type.