溃疡性结肠炎并发血栓栓塞性疾病15例临床特点分析

Analysis of clinical characteristics of 15 cases of ulcerative colitis patients with thromboembolic disease

目的:探讨溃疡性结肠炎(UC)与血栓栓塞性疾病(TEs)的关系。方法:分析15例UC并发TEs的临床特点。结果:患者平均年龄56.06岁;其中,合并肺栓塞8例,合并脑栓塞3例,肠系膜血栓栓塞4例。伴高血压、高血脂、冠心病、糖尿病等与动脉硬化有关的因素11例(73.3%)。结论:对于UC伴有动脉硬化有关因素及有梗死病史患者,尤其合并急性感染者,应认识到并发急性血栓性疾病的危险,慎用治疗UC的每种药物,及时抗凝治疗。

Objective:To explore the relationship between ulcerative colitis(UC) and thromboembolic disease(TEs).Methods:We analyzed the clinical features of 15 cases of ulcerative colitis patients with thromboembolic disease.Results:The average age of the patients was 56.06 years.There were 8 cases with pulmonary embolism,3 cases with cerebral embolism,and 4 cases with mesenteric embolism.11 cases(73.3%) had the factors of hypertension,hyperlipidemia,coronary heart disease and diabetes mellitus associated with atherosclerosis.Conclusion:For patients with ulcerative colitis and the factors associated with atherosclerosis and history of infarction,especially those with acute infection.We should recognize the risk of complicating acute thrombotic diseases,and carefully use every drug about UC,and prevent anticoagulant therapy in time.