奥曲肽治疗原发性肝癌并发上消化道出血的疗效探讨

The Therapeutic Effect of Octreotide in the Treatment of Primary Hepatic Carcinoma With Upper Gastrointestinal Hemorrhage

目的对奥曲肽治疗原发性肝癌并发上消化道出血的疗效进行探讨。方法选取88例原发性肝癌并上消化道出血患者,随机分为实验组与对照组,各44例;实验组采用奥曲肽治疗,对照组采用垂体后叶素治疗。结果实验组的治疗总有效率为95.45%,对照组为70.45%;实验组的止血时间比对照组短;实验组的不良反应发生率为9.09%,对照组为36.36%;组间比较,P<0.05。结论应用奥曲肽治疗原发性肝癌并发上消化道出血效果理想,且具有止血快、不良反应少等优势。

Objective To explore the efficacy of octreotide in treating primary hepatic carcinoma with upper gastrointestinal hemorrhage. Methods 88 patients with primary hepatocellular carcinoma with upper gastrointestinal hemorrhage were selected, and were randomly divided into the experimental group and the control group, 44 cases in each group. The experimental group was treated with octreotide, and the control group was treated with hypophysis. Results The total effective rate was 95.45% in the experimental group and 70.45% in the control group. The hemostatic time of the experimental group was faster compared with the control group. The incidence of adverse reactions was 9.09% in the experimental group and 36.36% in the control group, P 〈 0.05. Conclusion The application of octreotide in the treatment of primary hepatic carcinoma complicated with upper gastrointestinal hemorrhage is ideal, and it has the advantages of hemostasis and low adverse reaction.