清胃汤剂联合西药三联治疗耐药幽门螺杆菌感染相关胃病

Qingwei Decoction Combined With Western Medicine Triple Therapy in the Treatment of Helicobacter Pylori Infection Related Gastropathy

目的观察清胃汤剂联合西药三联治疗耐药幽门螺杆菌感染相关胃病的临床效果。方法选取2015年1月—2017年1月我院耐药幽门螺杆菌感染相关胃病患者346例,以随机的方式进行分组,对照组采用西药三联治疗,观察组采用清胃汤剂联合西药三联治疗,每组患者各173例,比较两组症状学积分和病理学积分、不同时间点Hp阳性率。结果观察组患者症状学积分(5.16±1.32)分;病理学积分(4.03±1.02)分,与对照组相比差异有统计学意义(P<0.05)。观察组患者幽门螺杆菌清除率较高,与对照组相比差异有统计学意义(P<0.05)。结论采用清胃汤剂联合西药三联治疗耐药幽门螺杆菌感染相关胃病患者,能够有效改善其临床症状,且效果十分显著。

Objective To observe the clinical effect of Qingwei decoction combined with western medicine triple therapy in the treatment of Helicobacter pylori infection related gastropathy. Methods 346 cases of gastric disease related to Helicobacter pylori infection in our hospital from January 2015 to January 2017 were selected. In a random manner, they were divided into two groupos. The control group was treated with western medicine, and the observation group was treated with the combination of Qingwei Decoction and Western medicine,173 cases in each group. The score of symptomatology, the integral of pathology and the positive rate of Hp at different time points were compared. Results The score of symptom score （5.16 ± 1.32） and pathological score （4.03 ± 1.02） in the observation group were significantly different from those in the control group （P 〈 0.05）. The clearance rate of Helicobacter pylori was higher in the observation group, and the difference was statistically significant compared with the control group （P 〈 0.05）. Conclusion Qingwei decoction combined with western medicine in the treatment of Helicobacter pylori infection related gastropathy patients can effectively improve its clinical symptoms, and the effect is very significant.