左氧氟沙星治疗老年社区获得性下呼吸道感染的效果分析

Effect of levofloxacin on elderly community acquired lower respiratory tract infection

目的:探讨左氧氟沙星治疗老年社区获得性下呼吸道感染的临床效果。方法:将我院收治的104例老年社区获得性下呼吸道感染患者为研究对象,观察组患者给予500 mg/100 ml左氧氟沙星氯化钠注射液治疗,对照组患者给予200 mg/100 ml左氧氟沙星氯化钠注射液治疗。结果:观察组与对照组患者的临床治疗总有效率分别为94.2%和80.8%,细菌清除率分别为93.0%和76.2%,差异有统计学意义(P<0.05);观察组与对照组的不良反应发生率分别为5.77%和7.69%,差异无统计学意义(P>0.05)。结论:应用大剂量500 mg左氧氟沙星静脉滴注治疗老年社区获得性下呼吸道感染患者,可以有效提高患者的临床治疗效果,不良反应少,安全性高。

Objective： To explore the clinical effect of levofloxacin on the treatment of elderly community acquired lower respiratory tract infection. Methods： Patients with elderly community acquired lower respiratory tract infection in our hospital were selected as subjects. Patients in the observation group were treated with 500 mg/100 ml levofloxacin and sodium chloride injection,while patients in the control group were admistered with 200 mg/100 ml levofloxacin and sodium chloride injection. Results： The total efficiency of the observation group and control group were 94. 2% and 80. 8% respectively,and the bacterial clearance rates were 93. 0% and 76. 2% respectively,which were of statistical differences（ P〈0.05）. The total adverse reaction rates of the observation group and the control were 5. 77% and 7. 69%respectively,which were of statatistical differences（ P〉0. 05）. Conclusion： Application of large dose of levofloxacin with a dose of 500 mg to the treatment of elderly community acquired lower respiratory tract infection can effectively improve the clinical effect,reduce the incidence of adverse reactions. Besides,it is safe for patients.