静脉滴注加雾化吸入沐舒坦治疗新生儿肺炎的疗效分析

Curative effect of intravenous infusion and aerosol inhalation of ambroxol on treating neonatal pneumonia

目的:探讨静脉滴注加雾化吸入沐舒坦治疗新生儿肺炎的疗效。方法:将新生儿肺炎患者88例随机分为对照组和实验组,每组44例,对照组患儿常规沐舒坦静脉滴注治疗;实验组患儿沐舒坦静脉滴注联合雾化吸入,比较两组患儿的动脉血气、不良症状改善情况。结果:实验组Pa CO2在给药8 h、24 h后,各项指标低于对照组,差异有统计学意义(P<0.05)。实验组患儿肺部湿罗音完全消失时间为(4.58±1.31)d,低于对照组患儿(8.17±1.29)d(P<0.05),患儿咳嗽和气喘完全恢复时间也明显短于对照组(P<0.05)。结论:沐舒坦静脉滴注加雾化吸入对新生儿肺炎患者疗效优于单纯静脉滴注。

Objective： To investigate the curative effect of intravenous infusion and aerosol inhalation of ambroxol on the treatment of neonatal pneumonia. Methods： 88 cases of neonatal pneumonia were randomized into the control group and experimental group, with 44 cases in each group. Neonatal pneumonia patients in the control group were with conventional ambroxol intravenous infusion therapy,while patients in the experimental group were treated with ambroxol intravenous infusion combined with ambroxol inhalation. Then,arterial blood gas and the improvement of adverse symptoms were compared between patients in both groups. Results： 8 h and 24 h after treatment,all indexes of the Pa C02 in the experimental group was significantly lower than those in the control group,which were of statistical differences（ P〈0. 05）. The time required for the complete disappearance of lung moist rales in the experimental group was（ 4.58±1.31） d,lower than（ 8.17±1.29） d in the control group（ P〈0.05）,and the time of complete recovery of children＇s cough and asthma was also significantly lower than that in the control group（ P〈0. 05）. Conclusion： The treatment effects of ambroxol intravenous infusion combined with aerosol inhalation on neonatal pneumonia patients are better than those of single intravenous infusion.