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Formin' bridges between microtubules and actin filaments in axonal growth cones

Formin' bridges between microtubules and actin filaments in axonal growth cones
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摘要 It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule(MT)cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems(reviewed in Cammara-ta et al., 2016). It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule(MT)cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems(reviewed in Cammara-ta et al., 2016).
机构地区 Institute of Genetics
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第12期1971-1973,共3页 中国神经再生研究(英文版)
基金 supported by the Hungarian Science Foundation(OTKA)(K109330 to JM) the Hungarian Brain Research Program(KTIA_NAP_13-2-2014-0007 to JM) the National Research,Development and Innovation Office(GINOP-2.3.2-15-2016-00001 and GINOP-2.3.2-15-2016-00032 to JM) by an MTA Postdoctoral Fellowship(to IF)
关键词 Formin'' bridges axonal growth cones Formin'' bridges axonal growth cones
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