血府逐瘀汤联合阿托伐他汀对冠心病患者脂代谢的影响分析

Effect analysis of Xuefu Zhuyu decoction combined with atorvastatin on lipid metabolism in patients with coronary heart disease

目的探讨血府逐瘀汤联合阿托伐他汀对冠心病患者脂代谢的影响。方法 80例冠心病患者,随机分为试验组和对照组,各40例。两组患者均采取常规治疗,在此基础上试验组患者采取血府逐瘀汤联合阿托伐他汀治疗,对照组患者采取阿托伐他汀治疗。比较两组患者治疗后总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平。结果治疗后,试验组患者TC为(2.17±0.21)mmol/L、TG为(1.33±0.12)mmol/L、HDL-C为(1.08±0.17)mmol/L、LDL-C为(1.46±0.01)mmol/L,均优于对照组的(3.59±0.23)、(1.74±0.31)、(0.94±0.04)、(1.65±0.02)mmol/L,差异有统计学意义(P<0.05)。结论采用血府逐瘀汤联合阿托伐他汀治疗冠心病可以明显改善患者血脂,提高临床疗效,值得在临床推广。

Objective To discuss the effect of Xuefu Zhuyu decoction combined with atorvastatin on lipid metabolism in patients with coronary heart disease. Methods A total of 80 patients with coronary heart disease were randomly divided into experimental group and control group, with 40 cases in each group. Both groups received conventional therapy, and the experimental group was treated with Xuefu Zhuyu decoction combined with atorvastatin. The control group was treated with atorvastatin. Comparison were made on total cholesterol（TC）, triglyceride（TG）, high density lipoprotein cholesterol（HDL-C） and low density lipoprotein cholesterol（LDL-C） level after treatment between two groups. Results After treatment, the experimental group had TC as（2.17±0.21） mmol/L, TG as（1.33±0.12） mmol/L, HDL-C as（1.08±0.17） mmol/L and LDL-C as（1.46±0.01） mmol/L, which were all better than（3.59±0.23）,（1.74±0.31）,（0.94±0.04） and（1.65±0.02） mmol/L in the control group, and their difference was statistically significant（P〈0.05）. Conclusion Combination of Xuefu Zhuyu decoction and atorvastatin can obviously improve blood lipid and the clinical effect of patients with coronary heart disease. It is worthy of clinical promotion.