浅析抗生素治疗急性肺脓肿的临床效果以及对生活质量的影响

Analysis of clinical effect of antibiotic therapy in patients with acute pulmonary abscess, and its influence on quality of life

目的对急性肺脓肿患者接受抗生素治疗的临床效果进行研究分析,评价患者接受治疗后的安全性和生活质量改善情况。方法 72例急性肺脓肿患者,根据治疗方法不同分为对照组和试验组,各36例。对照组患者接受清热解毒法治疗,试验组患者接受抗生素治疗。比较两组患者治疗效果、生活质量及不良反应发生情况。结果试验组患者治疗总有效率为97.2%,高于对照组患者的77.8%,差异具有统计学意义(P<0.05)。试验组患者呼吸状况满意度为88.9%(32/36)、饮食满意度为94.4%(34/36)、工作状态满意度为91.7%(33/36),均高于对照组的58.3%(21/36)、69.4%(25/36)、61.1%(22/36),差异具有统计学意义(P<0.05)。试验组不良反应发生率为13.9%,低于对照组的33.3%,差异具有统计学意义(P<0.05)。结论急性肺脓肿患者接受抗生素治疗安全可靠,生活质量改善明显,可以推广使用。

Objective To study and analyze the clinical effect of antibiotic therapy in patients with acute lung abscess, and its influence on quality of life, and evaluate the safety and quality of life improvement after treatment. Methods A total of 72 patients with acute pulmonary abscess were divided by different treatment methods into control group and experimental group, with 36 cases in each group. The control group was treated with Qingre Jiedu formula, and the experimental group was treated with antibiotic therapy. Comparison were made on treatment effect, quality of life and occurrence of adverser reactions between two groups. Results The experimental group had higher total treatment effective rate as 97.2% than 77.8% in the control group, and the difference was statistically significant（P〈0.05）. The experimental group had satisfaction of respiratory condition as 88.9%（32/36）, dietary satisfaction as 94.4%（34/36）, satisfaction of working condition as 91.7%（33/36）, which were all higher than 58.3%（21/36）, 69.4%（25/36） and 61.1%（22/36） in the control group, and their difference was statistically significant（P〈0.05）. The experimental group had lower incidence of adverse reactions as 13.9% than 33.3% in the control group, and the difference was statistically significant（P〈0.05）. Conclusion Antibiotic therapy is safe and reliable for acute pulmonary abscess patients, and can obviously improve their quality of life. It can be promoted and applied.