婴幼儿眼部血管瘤的治疗进展

Advances in the treatment of periorbital infantile hemangiomas

血管瘤是婴幼儿时期最常见的眼部良性肿瘤,好发于眼睑和眶周部位。病变可因上睑下垂遮挡视轴,或眼球移位散光,影响患儿视力发育。婴幼儿血管瘤的治疗需要掌握恰当的时机和适应症,并结合这一时期的生理发育特点,选择合适的干预手段。目前常用的治疗方法包括口服药物治疗(如β受体阻滞剂、糖皮质激素)、外用药物治疗(β受体阻滞剂、免疫调节剂)、局部药物注射治疗(糖皮质激素、硬化剂、α干扰素)、以及激光和手术治疗。本文对上述婴幼儿眼部血管瘤的治疗方法和进展予以综述。

Periorbital infantile hemangiomas（ IHs） are considered the most common type of orbital benign tumor in infancy. Eyelids and the periorbital areas are frequently involved. Periorbital IH may cause visual axis obstruction,global displacement or astigmatism. Non-treated lesions may impair normal visual development. Thus,appropriate and timely therapeutic procedures are required. Selection of treatment should take children＇s growth and development characteristics into consideration. Current treatment modalities include oral medicine（ e. g.,β-blocker,corticosteroids）,topical medicine（ e. g.,β-blocker and immunomodulator ointment for external use）,intralesional injection（ e. g.,corticosteroids,sclerosants,α-interferon）,laser therapy and surgical resection. This article reviewed the therapeutic methods and advances in the treatment of periorbital IH.