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中晚期卵巢癌综合治疗的临床疗效观察 被引量:4

Observation of the clinical effects of comprehensive treatment of middle and late ovarian cancer
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摘要 目的观察、分析中晚期卵巢癌综合治疗的临床疗效。方法选取徐州医科大学附属医院妇科中晚期卵巢癌患者60例,行肿瘤细胞减灭术联合化疗的综合治疗,分析其临床疗效。结果综合治疗后,Ⅱ期卵巢癌患者的5年生存率为50.00%,Ⅲ期卵巢癌患者为47.50%,2组的差异无统计学意义(P〉0.05);经肿瘤细胞减灭术后无残留病灶患者的5年生存率为57.89%,而残留病灶在1cm及以下的患者为31.82%,2组的差异有统计学意义(P〈0.05);化疗8个疗程的中晚期卵巢癌患者的5年生存率为61.54%,而化疗疗程不满8个的中晚期卵巢癌患者为33.33%,2组的差异有统计学意义(P〈0.05)。结论综合治疗的疗效与卵巢癌的临床分期无明显关联性;肿瘤细胞减灭术后病灶的残留情况对疗效有显著影响;化疗达8个疗程,则患者的5年生存率增高。 Objective To observe and analyze the clinical efficacy of comprehensive treatment of middle and late o- varian cancer. Methods A total of 60 middle and late ovarian cancer patients in our department were selected to under- go comprehensive treatment including tumor reductive surgery and chemotherapy before efficacy analysis. Results After comprehensive treatment, the 5 -year survival rate was 50.00% for ovarian cancer patients at phase Ⅱ , and 47.50% for those at phase m, without statistical difference ( P 〉 0.05 ). After tumor reductive surgery, the 5 - year survival rate was 57.89% for patients without residual lesions, which was remarkably different from 31.82% for those with ~〈 1 em residual lesions ( P 〈 0.05 ). Furthermore, the 5 - year survival rate was 61.54% for middle and late ovarian cancer pa- tients after 8 treatment durations of chemotherapy, which was remarkably different from 33.33 % for those receiving chem- otherapy less than 8 treatment durations ( P 〈 0.05 ). Conclusions There is no significant relationship between the effi- cacy of comprehensive treatment and the clinical stage of ovarian cancer. The residual lesions after tumor reductive sur- gery can greatly affect efficacy. Patients show a high 5 - year survival rate after 8 treatment durations of chemotherapy.
出处 《徐州医科大学学报》 CAS 2017年第12期799-801,共3页 Journal of Xuzhou Medical University
关键词 中晚期卵巢癌 肿瘤细胞减灭术 化学治疗 临床疗效 middle and late ovarian cancer tumor reductive surgery chemotherapy clinical efficacy
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