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腹腔镜下肾部分切除术治疗肾未分化肉瘤临床观察

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摘要 【目的】探讨腹腔镜下肾部分切除术治疗肾未分化肉瘤临床疗效。【方法】回顾性分析l例肾未分化肉瘤患者的临床资料,根据其影像学资料及临床病理学特征。初步诊断为肾脏恶性肿瘤。患者行择期腹腔镜下肾部分切除术。根据患者临床资料对该疾病进行检索。复习相关文献并总结其诊治经验。【结果】患者行腹腔镜下肾部分切除术后恢复良好。病理HE染色显示肿瘤细胞呈多形性.圆形、梭形、多角形.可见多核巨细胞。免疫组化染色检查Vimentin、CD68、CD10、Cathepsin-K、Ki67等均阳性.诊断为肾未分化肉瘤。患者术后随访20个月.未见肿瘤复发。【结论】肾未分化肉瘤为临床罕见肾肿瘤.恶性程度高.病程进展快。确诊主要依靠免疫组化病理学检查.手术切除为首选治疗方法。
出处 《医学临床研究》 CAS 2017年第12期2465-2467,共3页 Journal of Clinical Research
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  • 1毕新刚,马建辉,赵平,徐昕,寿建忠,郑闪,何祖根,王明荣.散发性肾透明细胞癌VHL基因突变的研究[J].医学研究杂志,2006,35(5):16-18. 被引量:1
  • 2孙长成,孔垂泽,李泽良,王侠,杨春明.肾癌组织中Pten/MMAC1/Tep1的表达及临床意义[J].中华肿瘤防治杂志,2007,14(11):847-849. 被引量:3
  • 3Lee JT, McCubrey JA. BAY-43-9006 Bayer/Onyx. Curr Opin Investig Drugs, 2003, 4: 757-763.
  • 4Escudier B, Eisen T, Stadler WM, et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med, 2007, 356:125-134.
  • 5Wilhelm SM, Carter C,Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/ MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res, 2004, 64: 7099-7109.
  • 6Awada A, Hendlisz A, Git T, et al. Safety and pharmacokinetics of BAY 43 9006 administered for 21 days on/7 days off in patients with advanced, refractory solid tumours. Br J Cancer, 2005, 92: 1855-1861.
  • 7Ratain MJ, Eisen T, Stadler WM, et al. Phase Ⅱ placebo controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol, 2006, 24; 2505-2512.
  • 8Motzer RJ, Bacik J, Murphy BA, et al. Interferon-alpha as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oneol, 2002, 20, 289-296.
  • 9Knox JJ, Figlin RA, Stadler WM, et al. The Advanced Renal Cell Carcinoma Sorafenib (ARCCS) expanded access trial in North America: Safety and efficacy. J Clin Oneol, 2007, 25(Suppl) : 241.
  • 10Akaza H, Tsukamoto T, Murai M, et al. Phase Ⅱ study to investigate the efficacy, safety, and pharmacokinetics of sorafenib in Japanese patients with advanced renal cell carcinoma. JpnJ Clin Oncol, 2007, 37: 755-762.

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