中医艾灸配合抗结核药物对肺结核患者的临床疗效及其对γ-干扰素水平的影响

Clinical Efficacy and Influence on Gamma Interferon of Moxibustion Combined with Anti-tuberculosis Drugs in Patients with Tuberculosis

目的:评价中医艾灸配合抗结核药物对肺结核患者的临床疗效及其对γ-干扰素(γ-IFN)水平的影响。方法:选取2016年8月—2016年12月间收治的肺结核患者40例资料,采用随机分组法将患者分为治疗组和对照组,每组20例;对照组患者给予抗肺结核药物治疗,治疗组患者在对照组基础上加用电子中医艾灸治疗,评价两组患者治疗1月后的总有效率和痰涂片阴转率的差异,以及治疗前后临床症状改善的评分值和γ-IFN水平测得值的变化情况。结果:治疗组患者治疗后的总有效率为95.00%高于对照组为65.00%(P<0.05);两组患者治疗后各项症状的评分值均优于治疗前(P<0.05);治疗后治疗组患者的γ-IFN水平测得值高于对照组(P<0.05)。结论:采用中医艾灸配合抗结核药物治疗肺结核患者的疗效较为确切,有效改善了临床症状。

Objective： To evaluate tile clinical efficacy and influence on Gamma interferon（γ-IFN） of Moxibustion combined with anti-tuberculosis drugs in patients with tuberculosis（TB）. Methods： 40 patients TB were selected and treated during August 2016 to December 2016 in our hospital： they were divided into two groups randomly（treatment group and control group）, each group was enrolled in 20 patients. The control group was treated with conventional anti- tuberculosis chemotherapy; and the treatment group was treated with electronic moxibustion combined with anti-tuber- culosis chemotherapy. The total effective rate, the difference in the negative rate of sputum smear, the improvement of the score of clinical symptoms and the changes in the level of γ-IFN 1 month alter treatment between the two groups were evalued. Results： The total effective rate of treatment group was 95.00%, compared with 65.00% in the control group, with significant difference between the two groups （P〈0.05）. Alter treatment, the symptoms of the two groups were significantly improved, compared with the control group, the symptom scores of improved appetite were signifi- cantly different （P〈 0.05）. The level of γ-IFN in the treatment group was statistically higher than that of the control group （P〈 0.05）. Conclusion： Moxibustion therapy can effectively improve the clinical symptoms of patients and im- prove the clinical efficacy. The mechanism of moxibustion may be related to the adjustment ofy-lFN level.