“促愈熏洗方”对混合痔和低位单纯性肛瘘术后创面愈合的影响

Effect of “Cuyu Xunxi Formula” on postoperative wound healing of mixed hemorrhoids and simple low anal fistula

目的探究"促愈熏洗方"对混合痔和低位单纯性肛瘘术后创面愈合的影响。方法选取2013年12月~2015年12月在上海中医药大学附属曙光医院就诊的120例混合痔术后患者和144例低位单纯性肛瘘术后患者。采用高、低浓度,分长、短熏洗时间,在术后第3、7、14天观察创面疼痛、水肿、渗出和出血症状变化,通过多因素方差分析研究4个因素对术后症状积分的综合影响。结果两类疾病比较,药物对于术后疼痛影响差别不明显;术后第14天水肿、渗出改善程度以肛瘘为明显;出血在术后第7、14天两种疾病出现了差异。同时,术后第7天,稀释比例对两种疾病水肿改善有差异;熏洗时间对两种疾病渗出改善有不同。结论 "促愈熏洗方"在14 d的疗程中对于低位单纯性肛瘘术后症状的影响较大,在7 d的疗程中稀释比例和熏洗时间两个干预因素对于术后症状变化的影响较大。

Objective To investigate the effect of ＂Cuyu Xunxi Formula＂ on postoperative wound healing of mixed hemorrhoids and simple low anal fistula. Methods One humlred and twenty eases of postoperative patients with mixed hemorrhoids and 144 cases of postoperative patients with simple low anal fistula treated in Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from December 2013 to December 2015 were collected. By using high and low concentration, long and short time of fumigation, the changes of wound pain, edema, exudation and hemorrhage were observed after operation for 3, 7, 14 days, and the comprehensive effects of the four factors for postoperative symptom scores were analyzed by multi-factor analysis of variance. Results The effects of drugs on postoperative pain between the two diseases had no significant differences. The improvement degree of edema and exudation of anal fistula was most obvious on the 14th day after surgery. There was significant difference in terms of hemorrhage between the two diseases on the 7th and 14th day after surgery. Meanwhile, the dilution ratio had different effects on the improvement of edema between the two diseases on the 7th day after surgery, while the time of fumigation had different effects on the improvement of exudation of the two diseases. Conclusion ＂Cuyu Xunxi Formula＂ has great effects on postoperative symptoms of simple low anal fistula during the course of 14-day treatment, while dilution ratio and fumigation time have greater influences on the postoperative symptoms during the course of 7-day treatment.