卡前列素氨丁三醇治疗宫缩乏力性产后出血的临床效果

The clinical effect of patients with uterine atony postpartum hemorrhage in the treatment of Romethamine

目的探讨卡前列素氨丁三醇治疗宫缩乏力性产后出血的临床效果。方法选取2016年1月~2017年1月我院收治的84例宫缩乏力性产后出血患者作为研究对象,按照随机数字表法将其分为观察组和对照组,每组各42例。对照组患者给予常规治疗,观察组患者在常规治疗的基础上给予卡前列素氨丁三醇注射液进行治疗。比较分析两组患者的临床疗效、产后出血情况及不良反应发生情况。结果观察组患者的治疗总有效率为92.86%,明显高于对照组的76.19%,差异有统计学意义(P<0.05)。观察组患者的第三产程时间短于对照组,患者产后2、24 h出血量少于对照组,产后24 h血红蛋白下降值低于对照组,差异均有统计学意义(P<0.05)。两组患者出现不同程度的恶心、面色潮红、腹泻、血压升高等不良反应,观察组患者的不良反应总发生率为9.52%,明显低于对照组的26.19%,差异有统计学意义(P<0.05)。结论宫缩乏力性产后出血患者采用卡前列素氨丁三醇治疗,其临床疗效能够显著提升,产后出血情况得到明显改善,不良反应发生情况减少,值得临床推广应用。

Objective To investigate the clinical effect of patients with uterine atony postpartum hemorrhage in the treatment of Romethamine.Methods From January 2016 to January 2017,84 patients of uterine atony postpartum hemor- rhage treated in our hospital were selected as subjects and were randomly divided into observation group and control group according to the random table method,42 cases in each group.The control group was given conventional treat- ment,while the observation group was given Romethamine Injection on the basis of conventional treatment.The clinical efficacy,the postpartum hemorrhage and the adverse reactions of the two groups were compared and analyzed.Results The total effective rate of the observation group was 92.86%,which was significantly higher than that in the control group （76.19%）,the difference was statistically significant （P〈0.05）,The third stage of labor in the observation group was shorter than that in the control group,the amount of postpartum hemorrhage of 2 and 24 h were less than those in the control group,and the decrease of hemoglobin in postpartum 24 h was lower than that in the control group,the differ- ences were statistically significant （P〈0.05）.Two groups of patients showed different levels of nausea,flushing, diarrhea and elevated blood pressure rising,the total incidence of adverse reactions in the observation group was 9.52% ,which was significantly lower than 26.19% of the control group,the difference was statistically significant （P〈0.05）.Conclusion The clinical efficacy of patients with uterine atony postpartum hemorrhage in the treatment of Romethamine can be im- proved significantly,the postpartum hemorrhage improves and the incidence of adverse reactions decreases.h is worthy of clinical application.