三维超声自由解剖切面联合容积对比成像技术在胎儿胼胝体发育不良诊断中的应用价值

Application value of three-dimensional ultrasonographic omniview combined with volume contrast imaging in the diagnosis of fetal agenesis of the corpus callosum

目的探讨应用三维超声自由解剖切面联合容积对比成像技术诊断胎儿胼胝体发育不良的临床价值。方法选取2015年10月~2017年5月于我院进行产前检查的1054例胎儿作为研究对象,依次采取二维超声扫描、Omniview、Omniview联合VCI来观察胼胝体的显示效果及胼胝体发育不良诊断的准确性。结果二维超声检查对胼胝体的显示率为72.96%,单纯Omniview检查为89.66%,Omniview联合VCI检查术为98.96%,三种检查方法对胼胝体的显示率比较,差异有统计学意义(P<0.05)。以产后新生儿MRI检查结果作为金标准,二维超声诊断胼胝体发育不良的准确性为5.4%,单纯Omniview检查准确性为8.3%,Omniview联合VCI检查的准确性最高,可达81.2%,三种检查方法对胎儿胼胝体发育不良的诊断准确性比较,差异有统计学意义(χ~2=56.3,P<0.01)。结论应用三维超声自由解剖切面联合容积对比成像技术诊断胎儿胼胝体发育不良具有较好的显示效果和准确性。

Objective To investigate the clinical value of three-dimensional ultrasonographic omniview combined with volume contrast imaging （VCI） in the diagnosis of fetal agenesis of the corpus callosum.Methods From October 2015 to May 2017,1054 fetuses for prenatal examinations in our hospital were selected as subjects.They were performed with two-dimensional ultrasound seanning, nltrasonographic omniview and uhrasonographic omniview combined with VCI to observe the displayed effects of the corpus callosum and the accuracy of diagnosing agenesis of the corpus callosum. Results The display rate of corpus callosum of the two-dimensional ultrasound was 72.96%,uhrasonographic omniview was 89.66% and uhrasonographic omniview combined VCI was 98.96%.The display rate of corpus callosum were com- pared with three methods,and the differences were statistically significant （P〈0.05）.Postpartum neonatal MRI examina- tion results were used as gold standard,the accuracy of agenesis of corpus callosum in the two-dimensional ultrasound diagnosis was 5.4%,ultrasonographic omniview was 8.3%,the accuracy of uhrasonographic omniview combined with VCI was highest,at 81.2%.The accuracy of agenesis of corpus callosum were compared with three methods,and the differ- ences were statistically significant （x2=56.3,P〈0.01）.Conclusion Joint application of the three-dimensional uhrasono- graphic omniview combined with VCI in the diagnosis of fetal agenesis of the corpus callosum can obtain a remarkable effect and great accuracy.