三七水蛭粉按照3∶1配比治疗缺血性脑卒中临床疗效观察

Clinical observation of 37leech powder according to 3∶1 ratio in treating ischemic stroke

目的:观察三七水蛭粉按照3∶1配比治疗缺血性脑卒中患者的临床疗效。方法:共纳入缺血性脑卒中患者120例,将其按照随机方法分为对照组和观察组,每组60例。对照组予脑活素联合扎格雷钠针,1次/d静滴,观察组在脑活素联合扎格雷钠针基础上予三七粉和水蛭粉按照3∶1比例配制胶囊口服,治疗周期为2周。经治疗后观察并比较对照组及观察组临床疗效、NIHSS评分、血液流变学参数变化、CT体积检查结果。结果:观察组临床疗效明显优于对照组,两组比较有显著性差异(P<0.05),观察组NIHSS评分明显低于对照组(P<0.05),血液流变学参数比较,观察组与对照组有显著性差异(P<0.05),两组CT体积检查结果比较有显著性差异(P<0.05)。结论:三七水蛭按照3∶1配比治疗缺血性脑卒中疗效显著,值得在临床上推广。

Objective ： To observe the clinical efficacy of 37 leech powder according to 3 ： 1 ratio in the treatment of ische- mic stroke patients. Methods ： a total of 120patients with ischemic stroke were divided into control group and observation group according to random methods, each group had 60cases. The control group was treated with Cerebrolysin zagre sodium needle, 1/d intravenous drip combined with Cerebrolysin in the observation group given 37sodium zagre needle powder and leech powder according to the proportion of 3 ： 1 compound capsule for 2weeks. After treatment, the clinical efficacy, NIHSS score, hemorheological parameters and CT volume of the control group and the observation group were observed and compared. Results ： the clinical curative effect of observation group was significantly better than the control group, there were significant differences between two groups （ P〈0. 05 ）, the NIHSS score of the observation group was significantly lower than the control group （ P〈 0. 05 ）, hemorheological parameters, there was significant difference between the observation group and the control group （ P〈 0. 05 ）, two groups of CT volume inspection results there was significant difference （ P〈0. 05 ）. Conclusion ： 37, the treatment of ischemic stroke with leech in accordance with 3 ： 1 ratio is effective, worthy of clinical promotion.