期刊文献+

β_2受体激动剂与抗胆碱能药物治疗COPD临床疗效观察 被引量:1

下载PDF
导出
摘要 目的:分析探讨β_2受体激动剂与抗胆碱能药物治疗COPD的临床疗效。方法:对我院呼吸内科收治的200例慢性阻塞性肺疾病(COPD)病例采用随机双盲法进行随机分组研究,分为对照组(n=100)和观察组(n=100)。对照组给予常规对症治疗,观察组在常规治疗的基础上给予β_2受体激动剂联合抗胆碱能药物治疗。对比观察两组肺功能改善情况和临床疗效。结果:两组治疗后肺功能改善情况均优于治疗前;观察组治疗总有效率为92%,显著高于对照组的74%,具有显著差异(P<0.05);治疗后1S呼吸测定显示,观察组肺功能恢复情况优于对照组(P<0.05)。结论:COPD在临床常规对症治疗的基础上实施β_2受体激动剂与抗胆碱能药物治疗临床效果显著,有效改善肺功能,值得临床推广。
作者 马艳霞
出处 《北方药学》 2018年第1期113-114,共2页 Journal of North Pharmacy
  • 相关文献

二级参考文献89

  • 1陈建,王广发.慢性阻塞性肺疾病全球倡议2011修订版解读[J].中国医学前沿杂志(电子版),2012,4(1):42-44. 被引量:65
  • 2GOLD Executive Committee. Global strategy for the the diagnosis, management, and prevention of chronic obstructive pulmonary disease ( Revised 2011 ) [EB/OL]. [2012-01-16]. http://www.goldcopd. com.
  • 3Wedzicha JA, Calverley PM, $eemungal TA, et al. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am J Respir Crit Care Med, 2008,177: 19-26.
  • 4Jones PW, Harding G, Berry P,et al. Development and first validation of the COPD Assessment Test. Eur Respir J, 2009,34 : 648-654.
  • 5Calverley P, Pauwels R, Vestbo J, et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease:a randomised controlled trial. Lancet,2003,361:449 456.
  • 6Mahler DA, Wire P, Horstman D, et al. Effectiveness of flutieasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2002, 166: 1084-1091.
  • 7Hanania NA, Darken P, Horstman D,et al. The efficacy and safety of fluticasone propionate (250 microg)/salmeterol (50 microg) combined in the Diskus inhaler for the treatment of COPD. Chest, 2003,124: 834-843.
  • 8Burge PS, Calverley PM, Jones PW, et al. Randomised, double blind, placebo controlled study of flutieasone propionate in patients with moderate to severe chronic obstructive pulmonary disease:the ISOLDE trial. BMJ,2000, 320:1297-1303.
  • 9Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med, 2007,356 : 775-789.
  • 10Nannini L, Cares CJ, Lasserson TJ, et al. Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2007, (4) : CD003794.

共引文献30

同被引文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部