经桡动脉行冠状动脉介入术应用替罗非班使用弹力加压型止血器压迫时间的研究

Research on the Compression Time of the Elastic Compression Tourniquet with Tirofiban in PCI via Radial Artery

目的:探讨经桡动脉行PCI应用替罗非班患者,使用弹力加压型止血器适宜的压迫时间。方法:将150例经桡动脉行PCI应用替罗非班患者随机分为观察组和对照组,每组各75例,观察组压迫8 h,对照组压迫6 h。比较两组术后桡动脉穿刺部位出血情况和压迫止血并发症。结果:观察组和对照组穿刺切口出血发生率分别为4%和20%;局部血肿发生率分别为2.67%和14.67%,差异均有统计学意义(P﹤0.01);两组患者压迫止血并发症发生率比较,差异无统计学意义(P﹥0.05)。结论:PCI应用替罗非班,于术后8 h撤除止血器,能够减少桡动脉穿刺部位出血情况发生,提高止血成功率。

Objective： To investigate the proper compression time of using the elastic compression tourniquet in patients with tirofiban via radial artery PCI.Methods： A hundred and fifty patients undergoing PCI with tirofiban via radial artery were randomly divided into two groups： the observation group and the control group; 75 cases in each group.The observation group was oppressed for 8 hours,and the control group was oppressed for 6 hours.The bleeding of the radial artery puncture site and the complications of hemostasis by compression were compared between the two groups.Results： The puncture incision bleeding rates of the observation group and the control group were 4% and 20% respectively; the incidence of local hematoma were 2.67% and 14.67% respectively.The differences were statistically significant（P ﹤0.01）; There was no significant difference in the incidence of hemostasis complications between the two groups（P ﹥0.05）.Conclusion： The application of tirofiban in PCI and the removal of hemostatic device at 8 hours after operation can reduce the bleeding at the site of radial artery puncture and improve the rate of hemostasis.