延迟脐带结扎对足月儿血氧饱和度及健康状况的影响研究

Effects of delayed umbilical cord ligation on SpO_2 and health status of term newborns

目的探讨延迟脐带结扎对足月儿血氧饱和度(SpO_2)、血常规及光疗发生率的影响。方法选取湖南省妇幼保健院产科阴道分娩新生儿200例(2015年7月-2016年9月)进行回顾性研究,其中100例采用延迟脐带结扎方式(延迟组)、100例采用常规脐带结扎(常规组),监测并对比产后不同时间点两组新生儿SpO_2、血红蛋白、铁蛋白、红细胞压积的差异。结果产后1、5 min及10 min,延迟组新生儿的SpO_2水平均高于常规组(P<0.05);产后30 min、产后4 h,延迟组新生儿SpO_2水平与常规组比较差异无统计学意义(P>0.05);产后24 h、48 h及72 h的血红蛋白、红细胞压积水平比较,延迟组新生儿均高于常规组(P<0.05);延迟组产后发生光疗2.00%、贫血发生率1.00%,均显著低于常规组的15.00%、8.00%,两组比较差异具有统计学意义(P<0.05)。讨论延迟脐带结扎有利于提高足月儿SpO_2、血红蛋白、红细胞压积的水平,降低光疗及贫血发生率。

Objective To explore the effect of delayed umbilical cord ligation on the oxygen saturation （ SpO2）, the results of blood routine test and the incidence of phototherapy of term newborns. Methods During July 2015 and September 2016, a total of 200 vaginal delivery newborns were recruited from our hospital obstetric department. Among them, 100 cases were with delayed umbilical cord ligation （ delayed group） and 100 cases were with normal umbilical cord ligation （ routine group）. The levels of SpO2, ferritin, hemoglobin, and red blood cell hematocrit of these two groups at different time point after giving birth were analyzed retrospectively. Results The levels of SpO2 of delayed group at lmin, 5mins, and 10 mins after giving birth were significantly higher than that of control group （P 〈 0.05 ）. There was no statistical difference in the levels of SpO2 at 30 mins and 4h after giving birth between the delayed group and the routine group （P 〉 0.05 ）. The levels of hemoglobin and hematocrit of delayed group at 24h, 48h, and 72h after giving birth were significantly higher than that of routine group （P 〈 0.05）. The incidences of phototherapy and anemia of delayed group was 2% and 1% , respectively. They were significantly lower than that of routine group （ 15% and 8%, respectively） （P 〈 O. 05）. Conclusion Delayed umbilical cord ligation is helpful to improve the levels of SpO2, hemoglobin, hematocrit, and to reduce the incidence of phototherapy and anemia.