季节性短期冷刺激对育肥猪血液生化指标的影响

Effect of Seasonal Cold Short-Term Stimulation on Blood Biochemical Indicators,Levels of Immune Factors and Oxidation Index of Finishing Pigs

旨在研究季节性短期冷刺激对育肥猪血液生化指标、免疫因子水平以及抗氧化指标的影响。选取60头体质量为(116±5)kg的育肥猪,随机分为5组,每组12头。试验期间大幅降温,对猪群造成冷刺激。试验第9、13和25天每头猪前腔静脉采集血液,测定生化、免疫和抗氧化指标。结果表明,冷刺激导致育肥猪血清中胰岛素含量显著降低,谷丙转氨酶、谷草转氨酶、血清葡萄糖、生长激素、三碘甲状腺原氨酸、甲状腺素含量显著升高;冷刺激导致育肥猪血清中IgA、IgG、IgM和白细胞介素2(IL-2)含量显著降低,一氧化氮含量显著升高,并造成育肥猪免疫力下降;冷刺激导致育肥猪血液中谷胱甘肽过氧化酶、超氧化物歧化酶含量显著降低,皮质醇含量升高,并造成育肥猪抗氧化能力降低。表明季节性短期冷刺激能通过改变育肥猪部分血清生化指标导致猪只免疫力和抗氧化能力降低。

This study was conducted to explore the influence of seasonal cold short term stimulation on blood biochemical indexes,levels of immune factors and oxidation index of finishing pigs. Sixty pigs with body weight of （116±5） kg were selected and randomly assigned into 5 groups with 12 replicates in each group. During the trial period,the average temperature of pigsty decreased caused cold stimulation to herds. The results showed that cold stimulation significantly reduced insulin content,while serum alanine aminotransferase,aspartate aminotransferase,growth hormone,L glucose,three iodine thyroid and thyroid hormone significantly increased. Cold stimulation significantly reduced immunoglobulin a,g,m,interleukin 2 and increased nitric oxide,reduced immunity of fattening pigs. Cold stimulation significantly reduced Glutathione peroxidase,superoxide dismutase and increased cortisol,reduced the antioxidant capacity of fattening pigs. So seasonal cold short term stimulation change partial pig serum biochemical indexes,and reduce the immune system and antioxidant capacity.