清胃降逆方治疗肝胃郁热型反流性食道炎60例疗效观察

Clinical Observation of Qingwei Jiangni Decoction in treating 60 cases with liver-stomach heat retention type reflux esophagitis

目的:观察清胃降逆方治疗肝胃郁热型反流性食道炎(reflux esophagitis RE)的临床疗效。方法:将60例符合纳入标准的RE患者随机分为治疗组与对照组。治疗组给予清胃降逆方治疗,对照组给予多潘立酮片、雷贝拉唑治疗。疗程4周,观察患者4周后症状改善情况、胃镜下食道炎愈合情况及总有效率。结果:2组患者症状、胃镜下积分比较,治疗组优于对照组,差异有统计学意义(P<0.05)。治疗组总有效率为90.0%,对照组为76.8%,2组总有效率比较差异有统计学意义(P<0.05)。结论:清胃降逆方治疗肝胃郁热型RE疗效显著,值得临床推广。

Objective： To observe the clinical effect of Qingwei Jiangni decoction in treating reflux esophagitis（RE）. Methods： Sixty RE patients who met the inclusion criteria were randomly divided into treatment group and control group. The treatment group was given Qingwei Jiangni Fang treatment, the control group was given domperidone tablets, rabeprazole treatment. After 4 weeks of treatment, the symptoms of the patients, the esophagitis healing under gastro- scope and the total effective rate were observed. Results： The symptom and score of gastroscopy in the two groups were better than that in the control group （P〈0.05）. The total effective rate was 90.0% in the treatment group and 76.8% in the control group. The total effective rate in the two groups was significantly different （P〈0.05）. Conclusion： Qingwei Ji- angni decoction has a significant effect in treating liver-stomach heat retention type reflux esophagitis, worthy of clini- cal promotion.