急性末端回肠炎与急性阑尾炎相关性研究

The correlation study between acute terminal ileitis and acute appendicitis

[目的]探讨急性末端回肠炎与急性阑尾炎的相关性。[方法]以行电子结肠镜检查的102例急性阑尾炎患者为研究对象,通过对临床、内镜及病理学检查结果,了解末端回肠炎发生情况,重点对比观察回盲瓣开放及闭合时间。[结果](1)102例急性阑尾炎患者中有58例(占6.86%)出现末端回肠急性炎症改变(急性末端回肠炎组),44例(占43.14%)未出现末端回肠炎症改变(正常末端回肠组);(2)急性末端回肠炎组中,出现回盲瓣溃疡27例,黏膜充血、糜烂改变13例;(3)急性末端回肠炎组插镜前的开放时间较正常末端回肠组明显延长,闭合时间明显缩短,差异有统计学意义(P<0.01);(4)急性末端回肠炎组插镜后回盲瓣开放时间进一步延长,差异有统计学意义(P<0.01),插镜前后闭合时间差异无统计学意义(P>0.05);(5)正常末端回肠组插镜后较插镜前回盲瓣开放时间亦延长,闭合时间缩短,差异均有统计学意义(P<0.01);(6)炎症程度越重,回盲瓣开放时间越长,闭合时间变化不明显(P<0.001)。[结论]急性阑尾炎时急性末端回肠炎显著增多,其原因可能与回盲瓣功能异常有关。

[Objective]To investigate the correlation between acute terminal ileitis and acute appendicitis. [Methods]A total of 102 patients with acute appendicitis underwent electronic colonoscopy in our hospital from January 2016 to September 2016 were selected as the research object. The opening and closing time of ileocecal valve were observed. [Results]（1）In the total 102 cases of acute appendicitis patients,58 cases had acute inflammation of the terminal ileum,accounting for 56.86%. （2）Among the 58 patients with acute inflammation of the terminal ileum, 27 cases had ileocecal valve ulcers. Mucosal hyperemia and erosions were found in 13 cases. （3）Compared with the control group, patients with acute terminal ileum inflammation had significantly longer opening time and shorter closing time of the valve before the insertion of the endoscope（P〈0.01）. （4）After the endoscope insertion,the opening time of the valve was still longer in acute terminal ileum inflammation patients than the controls, while the closing time showed no difference. （5）？？ （6）The severe the inflammation was,ileocecal valve opening time was longer after the endoscope insertion（P〈0. 01）. [Conclusion]Acute terminal ileitis is associated with a significant increase in acute appendicitis,and the cause may be related to the abnormal function of ileocecal valve.