大肠息肉发病相关危险因素Logistic分析

Analysis of the risk factors related with colon polyps pathogenesis

[目的]探讨大肠息肉的发病相关危险因素。[方法]收集行结肠镜检查的216例患者的临床资料,根据镜下有无发现大肠息肉分为息肉组和对照组,依序对息肉组和对照组患者的一般情况、生活习惯、生化指标、基础疾病中的18个变量进行检测。逐步筛选出大肠息肉发生的危险因素。[结果]息肉组与对照组间性别、年龄、烟酒史、冠心病、脂肪肝、尿酸、总胆固醇、三酰甘油、高密度脂蛋白、低密度脂蛋白、C-反应蛋白、癌胚抗原及幽门螺杆菌感染等比较差异有统计学意义(P<0.05)。Logistic回归分析提示年龄、饮酒、三酰甘油、幽门螺杆菌感染与大肠息肉的发生有关(P<0.05)。[结论]年龄、饮酒、三酰甘油、幽门螺杆菌感染为大肠息肉的发病危险因素。

[Objective]To investigate the clinical related risk factors for colon polyps. [Methods]The clinical data of 216 patients receiving colonoscopy were collected. The patients were divided into polyp group and non polyp patients. The living habits, biochemical indexes, underlying diseases of 18 variables in the two groups were analyzed. The risk factors for the occurrence of colon polyps were gradually selected. [Results]The gender, age, smoking history, coronary heart disease, fatty liver, uric acid, total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, C-reactive protein, carcinoembryonic antigen and Helicobacer pylor infection between the two groups showed significant differences（P〈0.05）. Logistic regression analysis indicated that age, alcohol consumption, triglyceride and Helicobacter pylori were the risk factors for colon polyps （P 〈 0.05）. [Conclusion] Age, alcohol consumption, triglyceride and Helicobacter pylori are risk factors for colon polyps.