肺癌患者化疗前后症状群的调查研究

Research of Symptom Clusters of Patients with Lung Cancer Before and After Chemotherapy

目的调查肺癌患者接受化疗前后的症状群种类及症状组成,并分析其变化,为开展肺癌化疗患者症状管理提供依据。方法采用便利抽样法,应用安德森症状评估量表中文版(the Chinese version of the MD Anderson symptom inventoryMDASI-C)、修订版肺癌特异症状模块,对102例准备接受化疗的肺癌患者进行问卷调查。结果肺癌患者在化疗前后均经历多重症状困扰,持续存在的症状为疲劳和睡眠不安。通过探索性因子分析提取症状集群,化疗前后均存在的症状群为:心理症状群、肺癌特异症状群。化疗前评估得出胃肠道症状群,化疗后出现疲乏相关症状群和化疗相关症状群。结论肺癌患者化疗前后存在多个不同的症状群,对患者造成很大困扰。护士应针对患者采取系统的症状干预策略,有效管理症状群,改善患者的生活质量。

Objective To investigate the symptom clusters and symptoms of patients with lung cancer before and after chemotherapy,and to analyze its change in order to provide evidence for symptom management in lung cancer patients underwent chemotherapy.Methods By convenience sampling,a sample of 102 lung cancer patients undergoing chemotherapy were surveyed with the Chinese version of the MD Anderson symptom inventory(MDASI-C)and the revised lung cancer module.Results Lung cancer patients experienced multiple symptom distress both before and after chemotherapy,persistent symptoms were fatigue and disturbed sleep.Two consistent clusters were identified by using exploratory factor analysis,which were psychological symptom cluster,lung cancer specific symptom cluster.The gastrointestinal symptom cluster appeared before chemotherapy,where as the fatigue related symptom cluster and chemotherapy related symptom cluster was found after chemotherapy.Conclusion There are several different symptom clusters that cause great distress in patients with lung cancer before and after chemotherapy.Nurses should take systematic symptom intervention strategies,manage symptom clusters to improve patient's quality of life.