针刺配合口服裸花紫珠片治疗Ⅰ期内痔便血疗效观察

Therapeutic Observation of Acupuncture plus Oral Administration of Luohua Zizhu Tablets for Hemafecia in Stage Ⅰ Internal Hemorrhoid

目的观察针刺配合口服裸花紫珠片治疗Ⅰ期内痔便血的临床疗效。方法将116例Ⅰ期内痔便血患者随机分为治疗组和对照组,每组58例。治疗组采用针刺配合口服裸花紫珠片治疗,对照组采用单纯口服裸花紫珠片治疗。观察两组治疗前后便血评分、痔核充血情况评分及各项实验室指标(血小板、凝血酶时间)的变化情况,并比较两组临床疗效。结果治疗组总有效率为93.1%,对照组为84.5%,两组比较差异具有统计学意义(P<0.05)。两组治疗3、5、7 d后便血评分及痔核充血情况评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗3、5、7 d后便血评分及痔核充血情况评分与对照组比较,差异均有统计学意义(P<0.05)。两组治疗后各项实验室指标与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后各项实验室指标与对照组比较,差异均具有统计学意义(P<0.05)。结论针刺配合口服裸花紫珠片是一种治疗Ⅰ期内痔便血的有效方法。

Objective To observe the clinical efficacy of acupuncture plus oral administration of Luohua Zizhu tablets in treating hemafecia in stage Ⅰ internal hemorrhoid. Method A total of 116 patients with hemafecia in stage Ⅰ internal hemorrhoid were randomized into a treatment group and a control group, 58 cases each. The treatment group was intervened by acupuncture plus oral administration of Luohua Zizhu tablets, while the control group was treated with oral administration of Luohua Zizhu tablets alone. The hemafecia score, hemorrhoid congestion score, and laboratory indexes （platelet and thrombin time） were observed before and after the treatment. The clinical efficacies of the two groups were also compared. Result The total effective rate was 93.1% in the treatment group versus 84.5% in the control group, and the between-group difference was statistically significant （P〈0.05）. Respectively after 3 d, 5 d and 7 d treatment, the hemafecia and hemorrhoid congestion scores were significantly different from the scores before the treatment in both groups （P〈0.05）. There were significant differences in comparing the hemafecia and hemorrhoid congestion scores between the two groups respectively after 3 d, 5 d and 7 d treatment （P〈0.05）. The laboratory indexes showed significant changes after the treatment in both groups （P〈0.05）. After the intervention, the laboratory indexes of the treatment group were significantly different from those of the control group （P〈0.05）. Conclusion Acupuncture plus oral administration of Luohua Zizhu tablets is an effective method in treating hemafecia in stage Ⅰ internal hemorrhoid.