欣母沛与米索前列醇预防行剖宫产术的高危孕妇产后出血的临床应用比较

Comparison of clinical application of hemabate and misoprostol in the prevention of postpartum hemorrhage in high risk pregnant women undergoing cesarean section

目的:比较欣母沛与米索前列醇在预防行剖宫产术的高危孕妇产后出血中的作用。方法:按随机数字表法,将本院所收治的行剖宫产术的高危孕产妇68例分成甲、乙两组。分别予以欣母沛、米索前列醇,比较两组预防产后出血的效果。结果:甲组产后出血发生率(5.9%)显著低于乙组(17.6%),差异有统计学意义(P<0.05);甲组产后2 h出血量、产后24 h出血量均低于乙组,差异有统计学意义(P<0.05)。结论:相较于米索前列醇,对行剖宫产术的高危孕产妇予以欣母沛治疗,可有效预防产后出血。

Objective：To compare the effect of hemabate and misoprostol in the prevention of postpartum hemorrhage in high risk pregnant women undergoing cesarean section.Methods：68 cases of high risk pregnant women undergoing cesarean section were selected and divided into the A group and the B group.They were treated with hemabate and misoprostol respectively.The effect of prevention of postpartum hemorrhage was compared between the two groups.Results：The incidence of postpartum hemorrhage in the group A（5.9%）was significantly lower than the group B（17.6%）,and the difference was statistically significant（P〈0.05）.A 2 h postpartum hemorrhage,postpartum hemorrhage and 24 h of the group A were lower than the group B,and the difference was statistically significant（P〈0.05）.Conclusion：Compared with misoprostol,hemabate is effective to prevent postpartum hemorrhage in high risk pregnant women undergoing cesarean section.