ELISA检测血清抗烟曲菌IgE和IgG在变应性曲菌病的诊断意义

Diagnostic Significance of Serum IgE-Af and IgG-Af Determined by ELISA in Allergic Bronchopulmonary Aspergillosis

用ELISA双抗体技术,测定11例变应性曲菌病患者血清中的抗烟曲菌的IgE和IgG其OD值为烟曲菌发试阳性的支气管哮喘患者的2倍以上。实验结果提示以本法检测血清抗烟曲菌的IgE和IgG特异抗体,对本病的早期诊断、随访观察以及与烟曲菌所致的哮喘的区别诊断有一定临床应用价值。

IgE--Af and IgG--Af measured by the ELISA double--antibody technique in sera from 11 patients with ABPA were elevated to at least twice that in sera from aschma patients with positive skin tests to Af. This suggests that serum IgE--Af and IgG--Af measured by this technique have a practical value for the early diagnosis and follow--up of ABPA, as well as for differentiating patients with ABPA from asthma patients with positive skin tests to Af.