慢性病长期用药处方开展情况的英文文献分析

Analysis on English Literature of Prescription Refills for Chronic Diseases

目的:本文检索关于慢性病长期用药处方的英文文献并进行系统评价,探索其取药模式和管理举措,以期为我国开展慢性病药物治疗管理和相关服务提供借鉴。方法:在Pub Med数据库中检索2016年4月以前发表的与长期用药处方相关的文献。对文献发表年份、国家/地区、涉及药物类型等信息进行分类分析。结果:美国、英国、瑞典是研究长期用药处方最多的国家,高血压、糖尿病、高脂血症等慢性病治疗药物是被提及最多的药物类型。年龄、受教育程度、种族、语言、药物类型等等都是影响患者依从性的因素。药师在长期用药处方项目中发挥审核、干预和随访等作用。结论:长期用药处方项目在欧美国家已发展成熟,管理有序。我国引入长期用药处方项目,是解决病情稳定的慢性非传染病患者的取药需求和长期药物治疗需求的良策。

Objective： To search the English literatures on prescription refills for chronic diseases for a systemic analysis and to explore the mode and the management measures in order to develop the prescription refill and medication therapy management service for patients with chronic diseases in China. Methods： In the pubmed database, the literatures related to prescription refills published before April 2016 was retrieved. The literatures were analyzed by classification of country or region, the types of drugs and the other in- formation. Results： It was found that the United States, Britain and Sweden were the countries with the most prescription refills. The medications for hypertention, diabetes, hyperlipidemia and other chronic diseases respectively were the most types of medications men- tioned. Age, educational level, race, language, type of medication, and so on. were the factors that affected patient compliance. Pharmacists played a role in auditing, intervention and follow-up in prescription refills programs. Conclusion： The programs of pre- scription refills is well developed in America and Europe, which may be a good way to solve the demand in long-term caremedication therapy for those patients in China.