催化炔烃马氏水合反应研究进展

Advances in the Catalytic Markovnikov Hydration of Alkynes toward Ketones

羰基是有机合成中的重要骨架结构单元,而催化炔烃马氏水合为酮来构建羰基是环境友好、具有100%原子经济性的反应,也是近年来有机化学研究的热点之一.按催化剂分类总结了炔烃水合反应的研究进展以及催化炔烃水合反应的机理,并对今后催化炔烃水合反应的发展方向进行了展望.

Carbonyl group is one of the important building blocks in organic synthesis. The catalytic Markovnikov hydration of alkynes is an eco-friendly reaction with 100% atom economy to construct carbonyl compounds, and is one of hot spots of organic chemistry over recent years. Research progress concerning catalytic hydration of alkynes to ketones on the view of the types of catalysts, and catalytic mechanisms are concluded. Finally, the further development and challenge of catalytic hydration of alkynes are discussed.