肝婴儿型血管内皮瘤的临床与超声特征分析

Clinical and Ultrasonographic Features of Hepatic Infantile Hemangioendothelioma

目的探讨肝婴儿型血管内皮瘤(IHE)的常规超声表现特征。方法回顾性分析2010年1月至2016年10月在我院经手术或肝穿活检病理证实为IHE的患者,对其一般临床资料、常规超声声像图进行分析。结果 8例IHE患者中,男4例,女4例,年龄15d^3岁,其中年龄<3月者6例。7例为单发病灶,1例为多发病灶;病灶最长径(8.2±1.0)cm;声像图上表现以低回声(4例)、等回声病灶(3例)为主;病灶以边界清楚(7例)、形态规则(7例)为主;内部回声多表现为不均匀(4例),偶可见钙化和周边声晕。彩色多普勒超声显示内部可见点线状或较丰富的血流信号(6例),以静脉血流为主。结论 IHE发病年龄常小于3月龄,超声声像图上表现多为单发、边界清楚、形态规则的实性肿块,或瘤体内可出现钙化时应考虑到IHE的可能。

Objective To investigate the clinical manifestations and ultrasound features of hepatic infantile hemangioendothelioma （IHE）. Methods This study retrospectively analyzed the clinical features and ultrasound characteristics of 8 patients of IHE, whose diagnosis was confirmed by surgery or liver biopsy from January 2010 to October 2016. Results Among the eight IHE patients, the male-to-female ratio was 1 -＂ 1, with the mean age ranged from 15 d to 3 yr. , of which six individuals were younger than 3 months old. Seven patients had single lesion and one case was multiple. The average size of the lesions was （8.2±1.0） cm diameter. Hypoechoic （4 cases） and echogenic lesions （3 cases） were shown by echography, the lesions border and morphology were clearly defined in 7 cases. Furthermore, internal echoes were mostly inhomogeneous （4 cases）, and calcification or peripheral halo were even visible. Color Dopplar flow imaging （CDFI） showed internal visible line or more abundant blood flow signal in 6 cases, mainly to venous blood flow. Conclusion The age of onset for hepatic IHE seems less than three months. The echography with single lesion with clear border, regular solid mass or calcification in the tumor, should come to the possibility of IHE.