卒中高危因素人群颈动脉粥样硬化同脂蛋白(a)的关系及其体质分布特点

Relationship Between Carotid Atherosclerosis of Risk Factors of Stroke Crowd and Serum Lipoprotein ( a) and Physical Characteristics

目的：研究卒中高危因素人群血清脂蛋白（a）同颈动脉粥样硬化的关系,及高血清脂蛋白（a）的中医体质分布特点。方法：将医院体检科进行体检的人群进行卒中高危因素人群筛查,依据颈动脉彩超结果将卒中高危因素人群分为：颈动脉彩超正常组、内中膜增厚组、斑块形成组。结果：斑块形成组脂蛋白（a）水平较内中膜增厚组、颈动脉彩超正常组差异具有统计学意义（P〈0.05,P〈0.05）,脂蛋白（a）≥300 mg·L-1组以痰湿质、气虚质为特点。结论：脂蛋白（a）是卒中高危因素人群颈动脉异常的独立危险因素。气虚、痰湿体质因素是卒中高危人群出现脂蛋白（a）异常的易感体质因素。颈动脉粥样硬化是引起缺血性卒中重要危险因素,通过简便易行的检测方法或评估手段,及早的预测颈动脉粥样硬化发生的可能,对预防缺血性卒中发生具有重要意义。

Objective： To study the risk factors of stroke crowd’s serum lipoprotein（ a） relationship with carotid atherosclerosis,and high serum lipoprotein（ a） physical distribution characteristics of traditional Chinese medicine. Methods：The risk factors of stroke of crowd in hospital for physical examination were screened and according to the results of carotid artery colour,the risk factors of stroke were divided into the normal group,intima-media thickness group and plaque formation group. Results： The plaque formation group have the highest levels of serum lipoprotein（ a） comparing with intima-media thickness and the normal group with statistical significance（ P 〈 0. 05,P 〈 0. 05）. The serum lipoprotein（a） of 300 mg·L-1 is charaterized by phlegm-damp and qi-insufficiency constitutions. Conclusion： The serum lipoprotein（ a） is a risk factor of stroke crowd independent risk factors for carotid artery anomalies. Qi deficiency and phlegm-damp constitutions are susceptible factors of abnormal lipoprotein（ a）. Carotid atherosclerosis is an important risk factor for ischemic stroke. By simple detection method or means of evaluation,early to predict the possibility of carotid artery atherosclerosis occurs is of great significance to the prevention of ischemic stroke.