磷脂酰肌醇3-激酶催化亚基δ基因的研究进展

Advance research of phosphatidylinositol 3 - kinase catalytic delta gene

磷脂酰肌醇3-激酶催化亚基δ（PIK3CD）基因编码催化亚基p110δ，其在经典通路磷酸肌醇3激酶（PI3K）-蛋白激酶B（Akt）-哺乳动物雷帕霉素靶蛋白（mTOR）中具有重要的作用，日益受到人们的关注和有关学者的重视。但是目前国内对PIK3CD基因的研究不多，因此本文就近年来PIK3CD基因的研究进展进行综述，旨在加深人们对PIK3CD基因的认识和理解。

Phosphatidylinositol 3-kinase catalytic delta （PIK3CD） gene, which encodes p110δ, one of PI3K（Phosphatidylinositol 3-kinase） catalytic isoforms, plays an important role in the phosphatidylinositol 3 kinase （PI3K）-protein kinase B （Akt）-mammalian target of rapamycin （mTOR） pathway, and the relative scholars pay more and more attention to this gene. However, there is few research on PIK3CD gene in China. Therefore, this article aims to review the advance research of PIK3CD gene and deepen understanding of this gene for the people.