开颅术前凝血功能与伤情程度在颅脑创伤预后中的相关性研究被引量：1

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摘要目的分析开颅术前凝血功能与伤情程度在颅脑创伤预后中的相关性。方法选取颅脑创伤患者120例,在急诊开颅术前根据格拉斯哥昏迷评分(GCS)将患者分为轻型组、中型组和重型组,对比3组患者凝血功能指标。然后再根据患者伤后3个月的格拉斯哥预后评分(GOS),将患者分为预后良好组与不良组,对比2组患者的凝血功能指标。结果重型组患者PT、APTT较轻型组和中型组患者延长,D-二聚体增加明显,中型组患者D-二聚体较轻型组患者明显增加(P<0.05);中型组与轻型组患者PT、APTT比较无显著(P>0.05)。预后不良患者PT、APTT较良好组延长,Fbg增加,D-二聚体增加(P<0.05)。结论凝血功能指标能判断颅脑创伤患者病情程度及预后情况。

作者喻海广

机构地区抚州市第一人民医院

出处《基层医学论坛》 2018年第1期70-71,共2页 The Medical Forum

关键词颅脑创伤凝血功能伤情程度预后相关性

分类号 R651.15 [医药卫生—外科学]

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1戚佳飞,施小燕.急性颅脑外伤后凝血功能及D-二聚体变化的研究[J].中国医师杂志,2011,13(9):1261-1263. 被引量：15
2谢方民,姬广福,李和楼,牛立健,张新华,曹春光.颅脑损伤急性期凝血指标和D-二聚体变化临床观察[J].泰山医学院学报,2010,31(5):329-331. 被引量：5

二级参考文献18

1李钢,徐如祥,柯以铨.颅脑损伤后凝血紊乱研究的新进展[J].中华神经医学杂志,2006,5(6):646-648. 被引量：22
2Allard CB,Scarpelini S,Rhind SG,et al.Abnormal coagulation tests are associated with progression of traumatic intracranial hemorrhage[J].J Trauma.2009,67(5):959-967.
3Pereira EA,Green AL,Chandran H,et al.Disseminated intravascular coagulation after isolated mild head injury[J].Acta Neurochir (Wien),2009,151(11):1521-1524.
4Halpern CH,Reilly PM,Trutz,AR,et al.Traumatic coagulopathy:the effect of brain injury[J].J Neurotrauma,2008,25(8):997-1001.
5Cohen MJ,Brohi K,Ganter MT,et al.Early coagulopathy after traumatic brain injury:the role of hypoperfusion and the protein C pathway[J].J Trauma,2007,63(6):1254-1261;discussion1261-12 62.
6Vavilala MS,Dunbar PJ,Rivara FP,et al.Coagulopathy predicts poor outcome following head injury in children less than 16 years of age[J].J Neurosurg Anesthesiol,2001,13(1):13-18.
7Chiaretti A,Pezzotti P,Mestrovic J,et al.The influence of hemocoagulative disorders in the outcome of children with head injury[J].Pediatr Neurosurg,2001,34(3):131-137.
8Saggar V,Mittal RS,Vyas MC.Hemostatic abnormalities in patients with closed head injuries and their role in predicting early mortality[J].J Neurotrauma.2009,26(10):1665-1668.
9Zehtabchi S,Soghoian S,Liu Y,et al.The association of coagulopathy and traumatic brain injury in patients with isolated head injury[J].Resuscitation,2008,76(1):52-56.
10van derBom JG,BotsML,Haverkate F,et a.l Activation products of the haemostatic system in coronary,cerebrovascular and peripheral arterial disease[J].ThrombHaemost,2001,85(2):234-239.