大蒜治疗脑外伤后耐药肺炎克雷伯杆菌所致肺部感染的疗效

Efficacy of Garlic in the Treatment of Lung Infection Caused by Drug-resistant Klebsiella Pneumoniae after Traumatic Brain Injury

目的探讨大蒜在重型脑外伤后并发耐药肺炎克雷伯杆菌所致肺部感染患者中的疗效。方法选取重型颅脑损伤后合并耐药肺炎克雷伯杆菌所致肺部感染80例,随机分为观察组与对照组,每组各40例,按照常规方法给予抗菌药物抗感染治疗;观察组在对照组的基础上加用大蒜治疗,疗程均为14天。结果治疗后观察组临床有效率77.5%优于对照组52.5%(P<0.05)、细菌清除率观察组37.5%高于对照组17.5%(P<0.05)、观察组C、反应蛋白水平和降钙素原水平较对照组明显下降。结论大蒜辅助治疗脑外伤后耐药肺炎克雷伯杆菌所致肺部感染临床效果优越,临床上值得推广使用。

OBJECTIVE To investigate the curative effect of garlic in patients with lung infection caused by drug-resistant Klebsiella pneumoniae after severe traumatic brain injury. METHODS 80 cases of severe craniocerebral injury complicated with pulmonary in- fection caused by resistant Klebsiella pneumoniae, were randomly divided into control group 40 cases, given antibiotic anti infection treatment according to the conventional method; the observation group of 40 cases, with garlic treatment on the basis of the control group, patients were treated for 14 days. RESULTS After treatment, the clinical effective rate of observation group was 77.5%, 52.5% higher than the control group （P〈0.05）, the bacterial clearance rate were 37.5% higher than that of the control group 17.5% （P〈 0.05）, the levels of C-reactive protein and procalcitonin levels of the observation group compared with the control group decreased sig- nificantly. CONCLUSION Curative effect of garlic adjuvant treatment of traumatic brain injury with pulmonary infection caused by drug resistance Klebsiella pneumoniae was superior, which was worthy of promotion.